生殖发育毒理学、免疫毒理学、环境毒理学、食品毒理学
1. 国家重点研发计划课题,2017YFC1600203,基于毒作用机制和健康效应终点的食品稀土元素和添加剂的安全性评估,2018/01-2021/12,主持
2. 国家新药创制科技重大专项,2009ZX09301-010,综合性创新药物研究开发技术大平台(开云app体育 )—新药安全性评价平台,2009/01-2010/12,主持
3. 国家自然科学基金面上项目,82073586,2-乙酰基-4-(1,2,3,4-四羟基丁基)咪唑引起淋巴细胞减少作用及其机制研究,2021/01-2024/12,主持
4. 国家自然科学基金面上项目,81773466,矮壮素的生殖毒性及其影响睾酮合成的HPG轴调节机制研究,2018/01-2021/12,主持
5. 国家自然科学基金面上项目,81473002, 矮壮素的发育毒性及其GH-IGF轴调节机制研究,2015/01-2018/12,主持
6. 国家自然科学基金面上项目,81273112,TAK1介导激活辅助T细胞在三氯乙烯引发药疹样皮炎和免疫性肝损伤中的作用, 2013/01-2016/12,主持
7. 国家自然科学基金面上项目,30972501,信号转导通路和表观遗传模式在双酚A神经发育毒性中的作用,2010/01-2012/12,主持
8. 国家自然科学基金面上项目,30771821,植物雌激素与环境雌激素发育毒性的联合作用及其机制研究,2008/01-2010/12,主持
9. 国家自然科学基金青年项目,39600123,太阳光及紫外线照射诱发基因突变的分子机理,1997/01-1999/12,主持
10. 北京市自然科学基金面上项目,7182083,蓝光剥夺对情绪的影响及视黑质介导的内在光传导机制,2018/01-2020/12,主持
11. 北京市自然科学基金面上项目,7082054,双氢青篙素抗光变态反应性接触性皮炎的作用环节研究,2008/01-2010/12,主持
12. 北京市自然科学基金面上项目,5062025,丝裂原活化蛋白激酶信号通路在重金属低剂量兴奋中作用,2006/01-2008/12,主持
13. 北京市科技创新基地培育与发展专项,Z151100001615035,食品中化学物发育毒性作用评价方法及机制研究,2015/07-2016/07,主持
1. Qianqian Xiao1, Xiaohong Hou, Chenping Kang, Linglu Xu, Lilan Yuan, Zhe Zhao, Qinghe Meng, Jianjun Jiang, Weidong Hao*, Chlorocholine chloride induced testosterone secretion inhibition mediated by endoplasmic reticulum stress in primary rat Leydig cells,Toxicology Letters, 2021, 356 :161–171
2. Qianqian Xiao, Xiaohong Hou, Chenping Kang, Bayindala Xiagedeer , Hong Hu , Qinghe Meng , Jianjun Jiang, Weidong Hao*, Effects of prenatal chlorocholine chloride exposure on pubertal development and reproduction of male offspring in rats, Toxicology Letters, 2021, 351 :28–36
3. Bayindala Xiagedeer, Xiaohong Hou, Qi Zhang, Hong Hu, Chenping Kang, Qianqian Xiao, WeidongHao*, Maternal chlormequat chloride exposure disrupts embryonic growth and produces postnatal adverse effects, Toxicology, 2020, 442:152534
4. Xiaohong Hou, Hong Hu, Bayindala Xiagedeer, Pengmin Wang, Chenping Kang, Qi Zhang, Qinghe Meng, Weidong Hao*. Effects of chlorocholine chloride on pubertal development and reproductive functions in male rats, Toxicology Letters, 2020, 319:1-10.
5. Bayindala Xiagedeer, Chenping Kang, Xiaohong Hou, Hong Hu, Qianqian Xiao, Weidong Hao*,Chlormequat chloride promotes rat embryonic growth and GH-IGF-1 axis, Toxicology,429:1-9
6. Yao Pan, Xiaohong Hou, Qinghe Meng , Xiaohua Yang , Lanqin Shang, XuetaoWei , Weidong Hao*,The critical role for TAK1 in trichloroethylene-induced contact hypersensitivity in vivo and in CD4+ T cell function alteration by trichloroethylene and its metabolites in vitro,Toxicology and Applied Pharmacology,2019,381:1-14
7. Xiaohong Hou, Dan Huang, Qinghe Meng, Qi Zhang, Lixia Jia, Siqi Wang, Zhiyuan Cheng, Shuang Wu, Lanqin Shang, Jianjun Jiang, Weidong Hao*, Pubertal chlorocholine chloride exposure inhibits testicular testosterone synthesis by down-regulating steroidogenic enzymes,Toxicology Letters, 2018, 288:17-24
8. Dan Huang,Shuang Wu,Xiaohong Hou,Lixia Jia,Qinghe Meng,Hongqian Chu,Jianjun Jiang,Lanqin Shang,Weidong Hao*,The Skeletal developmental toxicity of chlormequat chloride and its underlying mechanisms,Toxicology,2017, 381:1-9
9. Hongqian Chu,Jing Shang,Ming Jin,Yueyue Chen,Yao Pan,Yuan Li,Xi Tao,Zhiyuan Cheng,Qinghe Me,Qian Li,Guang Jia,Tong Zhu,Weidong Hao*,Xuetao Wei*,Comparison of lung damage in mice exposed to black carbon particles and 1,4-naphthoquinone coated black carbon particles,Science of the Total Environment, 2017, 580:572-581
10. Hongqian Chu,Jing Shang,Ming Jin,Qian Li,Yueyue Chen,Hongpeng Huang,Yuan Li,Yao Pan,Xi Tao,Zhiyuan Cheng,Qinghe Meng,Guang Jia,Tong Zhu,Xuetao Wei*,Weidong Hao*,Comparison of lung damage in mice exposed to black carbon particles and ozone-oxidized black carbon particles,Science of the Total Environment, 2016, 573:303-312