| Title | Solvatochromic biosensor reveals conformational changes of single molecules in living cells |
| Authors | Bei Liu Nicholas K.Pinkin Frederico M.Pimenta Shiqiong Hu Saygin Gulec Timothy C.Elston Klaus M.Hahn |
| Affiliation | National Biomedical Imaging Center, Peking University School of Future Technology Department of Pharmacology, University of North Carolina at Chapel Hill School of Medicine Phitonex,Inc. Curriculum in Bioinformatics and Computational Biology, University of North Carolina at Chapel Hill Computational Medicine Program, University of North Carolina at Chapel Hill |
| Issue Date | 2-Dec-2022 |
| Publisher | 2022生物物理大会摘要集 |
| Abstract | <正>Revealing the activity or conformation while following the diffusion of individual proteins inside living cells is challenging, demanding biosensors that are sensitive,easy to deploy, and versatile. GTPases are switch-like enzymes that interact with downstream effectors only when they are in their GTP-bound conformation. |
| URI | http://hdl.handle.net/20.500.11897/672280 |
| Appears in Collections: | 待认领 |
