| Title | Gravity matters for the neural representations of action semantics |
| Authors | Xiong, Ziyi Tian, Yu Wang, Xiaosha Wei, Kunlin Bi, Yanchao |
| Affiliation | Beijing Normal Univ, State Key Lab Cognit Neurosci & Learning, Beijing 100875, Peoples R China Beijing Normal Univ, IDG McGovern Inst Brain Res, Beijing 100875, Peoples R China Beijing Normal Univ, Beijing Key Lab Brain Imaging & Connect, Beijing 100875, Peoples R China China Astronaut Res & Training Ctr, Natl Key Lab Human Factors Engn, Beijing 100094, Peoples R China Peking Univ, Sch Psychol & Cognit Sci, Beijing 100871, Peoples R China Beijing Key Lab Behav & Mental Hlth, Beijing 100871, Peoples R China Peking Univ, Peking Tsinghua Ctr Life Sci, Beijing 100871, Peoples R China Chinese Inst Brain Res, Beijing 102206, Peoples R China |
| Keywords | PRIMARY MOTOR CORTEX PARKINSONS-DISEASE SUBTHALAMIC NUCLEUS LANGUAGE METAANALYSIS COMPREHENSION ORGANIZATION KNOWLEDGE CONCRETE OBJECT |
| Issue Date | Jan-2023 |
| Publisher | CEREBRAL CORTEX |
| Abstract | The dynamic relationship between the neural representation of action word semantics and specific sensorimotor experience remains controversial. Here, we temporarily altered human subjects' sensorimotor experience in a 15-day head-down tilt bed rest setting, a ground-based analog of microgravity that disproportionally affects sensorimotor experiences of the lower limbs, and examined whether such effector-dependent activity deprivation specifically affected the neural processes of comprehending verbs of lower-limb actions (e.g. to kick) relative to upper-limb ones (e.g. to pinch). Using functional magnetic resonance imaging, we compared the multivoxel neural patterns for such action words prior to and after bed rest. We found an effector-specific (lower vs. upper limb) experience modulation in subcortical sensorimotor-related and anterior temporal regions. The neural action semantic representations in other effector-specific verb semantic regions (e.g. left lateral posterior temporal cortex) and motor execution regions were robust against such experience alterations. These effector-specific, sensorimotor-experience-sensitive and experience-independent patterns of verb neural representation highlight the multidimensional and dynamic nature of semantic neural representation, and the broad influence of microgravity (hence gravity) environment on cognition. |
| URI | http://hdl.handle.net/20.500.11897/669362 |
| ISSN | 1047-3211 |
| DOI | 10.1093/cercor/bhad006 |
| Indexed | SCI(E) |
| Appears in Collections: | 心理与认知科学学院 生命科学学院 |
