| Title | The distribution and structural fingerprints of metals from particulate matters (PM) deposited in human lungs |
| Authors | Zhang, Xiangyuan Wang, Shaodong Ling, Lan Hou, Guanyu Leng, Siwen Ma, Na Qiu, Mantang Li, Xiao Guo, Xuejun |
| Affiliation | Beijing Normal Univ, Sch Environm, State Key Lab Environm Simulat, 19 Xinjiekouwai St, Beijing 100875, Peoples R China Peking Univ, Peoples Hosp, Dept Thorac Surg, 11 Xizhimen South St, Beijing 100044, Peoples R China Tongji Univ, Sch Environm Sci & Engn, State Key Lab Pollut Control & Resource Reuse, 1239 Siping Rd, Shanghai 200092, Peoples R China |
| Keywords | AIR-POLLUTION SIMULATED LUNG EXPOSURE PARTICLES PM2.5 INFLAMMATION TOXICITY IRON ENCAPSULATION MORTALITY |
| Issue Date | 15-Mar-2022 |
| Publisher | ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY |
| Abstract | This work investigated the distribution and chemical fingerprints of 24 metals in particulate matter (PM) deposited in nonoccupational human lungs. Metals in the pulmonary PM can be grouped by the mean concentration as > 5 x 10(3) mu g/g (Al/Fe/Ca/Mg/Zn), 1-5 x 10(3) mu g/g (Ti/Ba/Pb/Mn), 0.2-1 x 10(3) mu g/g (Cu/Cr/As/V) and < 100 mu g/g (Ni/Sn/Cd/Sb). Three parameters (LFL, LR, EFP) were defined to predict different metal leaching behaviors. The leaching factor (LFL) of metals was 10-60 for Pb/Sb/Cd/Co/Cu and decreased to 1-2 for Ni/Cr/ Mg/Al/Fe. Metals showed a divergent extent of lung retention (LR), including high retention (LR > 10, Al/Cd/Cr/ Ba/Ni/Ti/Sn/V/Sb), moderate retention (2 |
| URI | http://hdl.handle.net/20.500.11897/654004 |
| ISSN | 0147-6513 |
| DOI | 10.1016/j.ecoenv.2022.113324 |
| Indexed | SCI(E) |
| Appears in Collections: | 人民医院 |
