| Title | Linking the Fasting Blood Glucose Level to Short-Term-Exposed Particulate Constituents and Pollution Sources: Results from a Multicenter Cross-Sectional Study in China |
| Authors | Tian, Yanlin Fang, Jianlong Wang, Feng Luo, Zhihan Zhao, Feng Zhang, Yi Du, Peng Wang, Jiaonan Li, Yawei Shi, Wanying Liu, Yuanyuan Ding, Enmin Sun, Qinghua Li, Chengcheng Tang, Song Yue, Xu Shi, Guoliang Wang, Bin Li, Tiantian Shen, Guofeng Shi, Xiaoming |
| Affiliation | Peking Univ, Sino French Inst Earth Syst Sci, Coll Urban & Environm Sci, Lab Earth Surface Proc, Beijing 100871, Peoples R China Chinese Ctr Dis Control & Prevent, Natl Inst Environm Hlth, China CDC Key Lab Environm & Populat Hlth, Beijing 100021, Peoples R China Nanjing Univ Informat Sci & Technol, Collaborat Innovat Ctr Atmospher Environm & Equipm, Jiangsu Key Lab Atmospher Environm Monitoring & Po, Nanjing 210044, Peoples R China Nankai Univ, Coll Environm Sci & Engn, State Environm Protect Key Lab Urban Ambient Air P, Tianjin Key Lab Urban Transport Emiss Res, Tianjin 300350, Peoples R China Peking Univ, Sch Publ Hlth, Dept Epidemiol & Biostat, Beijing 100191, Peoples R China |
| Keywords | SECONDARY AEROSOL CONTRIBUTION TYPE-2 DIABETES-MELLITUS AMBIENT AIR-POLLUTION SOURCE APPORTIONMENT INSULIN-RESISTANCE MATTER RISK PM2.5 INFLAMMATION PREVALENCE |
| Issue Date | Jun-2022 |
| Publisher | ENVIRONMENTAL SCIENCE & TECHNOLOGY |
| Abstract | Ambient PM2.5 (fine particulate matter with aerodynamic diameters < 2.5 mu m) is thought to be associated with the development of diabetes, but few studies traced the effects of PM2.5 components and pollution sources on the change in the fasting blood glucose (FBG). In the present study, we assessed the associations of PM2.5 constituents and their sources with the FBG in a general Chinese population aged over 40 years. Exposure to PM2.5 was positively associated with the FBG level, and each interquartile range (IQR) increase in a lag period of 30 days (18.4 mu g/m3) showed the strongest association with an elevated FBG of 0.16 mmol/L (95% confidence interval: 0.04, 0.28). Among various constituents, increases in exposed elemental carbon, organic matter, arsenic, and heavy metals such as silver, cadmium, lead, and zinc were associated with higher FBG, whereas barium and chromium were associated with lower FBG levels. The elevated FBG level was closely associated with the PM2.5 from coal combustion, industrial sources, and vehicle emissions, while the association with secondary sources was statistically insignificant. Improving air quality by tracing back to the pollution sources would help to develop well-directed policies to protect human health. |
| URI | http://hdl.handle.net/20.500.11897/649065 |
| ISSN | 0013-936X |
| DOI | 10.1021/acs.est.1c0886010172 |
| Indexed | SCI(E) |
| Appears in Collections: | 城市与环境学院 地表过程分析与模拟教育部重点实验室 公共卫生学院 |
