| Title | A randomized controlled study of remote computerized cognitive, neurofeedback, and combined training in the treatment of children with attention-deficit/hyperactivity disorder |
| Authors | Luo, Xiangsheng Guo, Xiaojie Zhao, Qihua Zhu, Yu Chen, Yanbo Zhang, Dawei Jiang, Han Wang, Yufeng Johnstone, Stuart Sun, Li |
| Affiliation | Peking Univ Sixth Hosp, Beijing, Peoples R China Peking Univ, Inst Mental Hlth, Beijing, Peoples R China Peking Univ, NHC Key Lab Mental Hlth, Beijing 100191, Peoples R China Peking Univ Sixth Hosp, Natl Clin Res Ctr Mental Disorders, Beijing 100191, Peoples R China Univ Wollongong, Sch Psychol, Wollongong, NSW, Australia Univ Wollongong, Brain & Behav Res Inst, Wollongong, NSW 2500, Australia Yangzhou Univ, Sch Educ Sci, Dept Psychol, Yangzhou, Jiangsu, Peoples R China Zhejiang Normal Univ, Sch Special Educ, Hangzhou, Peoples R China |
| Keywords | DEFICIT HYPERACTIVITY DISORDER SINGLE-CHANNEL ADHD EEG AD/HD PERFORMANCE SEVERITY |
| Issue Date | Feb-2022 |
| Publisher | EUROPEAN CHILD & ADOLESCENT PSYCHIATRY |
| Abstract | There is an increasing interest in non-pharmacological treatments for children with attention-deficit/hyperactivity disorder (AD/HD), especially digital techniques that can be remotely delivered, such as neurofeedback (NFT) and computerized cognitive training (CCT). In this study, a randomized controlled design was used to compare training outcomes between remotely delivered NFT, CCT, and combined NFT/CCT training approaches. A total of 121 children with AD/HD were randomly assigned to the NFT, CCT, or NFT/CCT training groups, with 80 children completing the training program. Pre- and post-training symptoms (primary outcome), executive and daily functions were measured using questionnaires as well as resting EEG during eyes-closed (EC) and eyes-open (EO) conditions. After 3 months of training, the inattentive and hyperactive/impulsive symptoms, inhibition, working memory, learning and life skills of the three groups of children were significantly improved. The objective EEG activity showed a consistent increase in the relative alpha power in the EO condition among the three training groups. Training differences were not observed between groups. There was a positive correlation between pre-training EO relative alpha power and symptom improvement scores of inattention and hyperactivity/impulsivity, as well as a negative correlation between pre-training inattention scores and change in EO relative alpha. This study verified the training effects of NFT, CCT, and combined NFT/CCT training in children with AD/HD and revealed an objective therapeutic role for individual relative alpha activity. The verified feasibility and effectiveness of home-based digital training support promotion and application of digital remote training. |
| URI | http://hdl.handle.net/20.500.11897/638644 |
| ISSN | 1018-8827 |
| DOI | 10.1007/s00787-022-01956-1 |
| Indexed | SCI(E) SSCI |
| Appears in Collections: | 第六医院 |
