| Title | Rational Design and Preparation of Functional Hydrogels for Skin Wound Healing |
| Authors | Hao, Ruinan Cui, Zhuoyi Zhang, Xindan Tian, Ming Zhang, Liqun Rao, Feng Xue, Jiajia |
| Affiliation | Beijing Univ Chem Technol, Beijing Lab Biomed Mat, Beijing, Peoples R China Beijing Univ Chem Technol, State Key Lab Organ Inorgan Composites, Beijing, Peoples R China Peking Univ Peoples Hosp, Trauma Ctr, Beijing, Peoples R China Peking Univ, Natl Trauma Med Ctr, Minist Educ, Key Lab Trauma & Neural Regenerat, Beijing, Peoples R China |
| Keywords | DOUBLE-NETWORK HYDROGEL INJECTABLE HYDROGEL ANTIBACTERIAL RELEASE SCAFFOLDS |
| Issue Date | 24-Jan-2022 |
| Publisher | FRONTIERS IN CHEMISTRY |
| Abstract | Skin wound healing often contains a series of dynamic and complex physiological healing processes. It is a great clinical challenge to effectively treat the cutaneous wound and regenerate the damaged skin. Hydrogels have shown great promise for skin wound healing through the rational design and preparation to endow with specific functionalities. In the mini review, we firstly introduce the design and construction of various types of hydrogels based on their bonding chemistry during cross-linking. Then, we summarize the recent research progress on the functionalization of bioactive hydrogel dressings for skin wound healing, including anti-bacteria, anti-inflammatory, tissue proliferation and remodeling. In addition, we highlight the design strategies of responsive hydrogels to external physical stimuli. Ultimately, we provide perspectives on future directions and challenges of functional hydrogels for skin wound healing. |
| URI | http://hdl.handle.net/20.500.11897/637763 |
| ISSN | 2296-2646 |
| DOI | 10.3389/fchem.2021.839055 |
| Indexed | SCI(E) |
| Appears in Collections: | 人民医院 |
