| Title | The Impact of Quarantine on Pain Sensation among the General Population in China during the COVID-19 Pandemic |
| Authors | Sun, Jie Zheng, Yong-Bo Liu, Lin Li, Shui-Qing Zhao, Yi-Miao Zhu, Xi-Mei Que, Jian-Yu Li, Ming-Zhe Liu, Wei-Jian Yuan, Kai Yan, Wei Liu, Xiao-Guang Chang, Su-Hua Chen, Xuan Gao, Nan Shi, Jie Bao, Yan-Ping Lu, Lin |
| Affiliation | Peking Univ Third Hosp, Pain Med Ctr, Beijing 100191, Peoples R China Peking Univ, Inst Mental Hlth, Hosp 6,Chinese Acad Med Sci,Res Unit 2018RU006, NHC,Key Lab Mental Hlth,Natl Clin Res Ctr Mental, Beijing 100191, Peoples R China Peking Tsinghua Ctr Life Sci, Beijing 100191, Peoples R China PKU, IDG, McGovern Inst Brain Res, Beijing 100191, Peoples R China Peking Univ, Natl Inst Drug Dependence, Beijing 100191, Peoples R China Peking Univ, Beijing Key Lab Drug Dependence, Beijing 100191, Peoples R China Peking Univ, Sch Publ Hlth, Beijing 100191, Peoples R China |
| Keywords | SOCIAL-ISOLATION EPIDEMIOLOGY HEMORRHAGE VARIABLES STATINS STRESS FORGET |
| Issue Date | Jan-2022 |
| Publisher | BRAIN SCIENCES |
| Abstract | During the pandemic era, quarantines might potentially have negative effects and disproportionately exacerbate health condition problems. We conducted this cross-sectional, national study to ascertain the prevalence of constant pain symptoms and how quarantines impacted the pain symptoms and identify the factors associated with constant pain to further guide reducing the prevalence of chronic pain for vulnerable people under the pandemic. The sociodemographic data, quarantine conditions, mental health situations and pain symptoms of the general population were collected. After adjusting for potential confounders, long-term quarantine (>= 15 days) exposures were associated with an increased risk of constant pain complaints compared to those not under a quarantine (Odds Ratio (OR): 1.26; 95% Confidence Interval (CI): 1.03, 1.54; p = 0.026). Risk factors including unemployment (OR: 1.55), chronic disease history (OR: 2.38) and infection with COVID-19 (OR: 2.15), and any of mental health symptoms including depression, anxiety, insomnia and PTSD (OR: 5.44) were identified by a multivariable logistic regression. Additionally, mediation analysis revealed that the effects of the quarantine duration on pain symptoms were mediated by mental health symptoms (indirect effects: 0.075, p < 0.001). These results advocated that long-term quarantine measures were associated with an increased risk of experiencing pain, especially for vulnerable groups with COVID-19 infection and with mental health symptoms. The findings also suggest that reducing mental distress during the pandemic might contribute to reducing the burden of pain symptoms and prioritizing interventions for those experiencing a long-term quarantine. |
| URI | http://hdl.handle.net/20.500.11897/637249 |
| DOI | 10.3390/brainsci12010079 |
| Indexed | SCI(E) |
| Appears in Collections: | 第三医院 第六医院 公共卫生学院 |
