| Title | Closed-Loop Transcutaneous Auricular Vagal Nerve Stimulation: Current Situation and Future Possibilities |
| Authors | Yu, Yutian Ling, Jing Yu, Lingling Liu, Pengfei Jiang, Min |
| Affiliation | Capital Med Univ, Beijing Shijitan Hosp, Acupuncture Dept, Beijing, Peoples R China Peking Univ, Sch Clin Med 9, Beijing, Peoples R China Shenzhen Tradit Chinese Med Hosp, Dept Gynecol, Shenzhen, Peoples R China Huazhong Univ Sci & Technol, Tongji Hosp, Dept Chinese & Western Med, Tongji Med Coll, Wuhan, Peoples R China Capital Med Univ, Beijing Shijitan Hosp, Dept Anesthesiol, Beijing, Peoples R China |
| Keywords | MAJOR DEPRESSIVE DISORDER LEVEL TRAGUS STIMULATION SOLITARY TRACT NEUROMODULATION HYPOTHALAMUS PROJECTIONS MODULATION NUCLEUS TAVNS PAIN |
| Issue Date | 4-Jan-2022 |
| Publisher | FRONTIERS IN HUMAN NEUROSCIENCE |
| Abstract | Closed-loop (CL) transcutaneous auricular vagal nerve stimulation (taVNS) was officially proposed in 2020. This work firstly reviewed two existing CL-taVNS forms: motor-activated auricular vagus nerve stimulation (MAAVNS) and respiratory-gated auricular vagal afferent nerve stimulation (RAVANS), and then proposed three future CL-taVNS systems: electroencephalography (EEG)-gated CL-taVNS, electrocardiography (ECG)-gated CL-taVNS, and subcutaneous humoral signals (SHS)-gated CL-taVNS. We also highlighted the mechanisms, targets, technical issues, and patterns of CL-taVNS. By reviewing, proposing, and highlighting, this work might draw a preliminary blueprint for the development of CL-taVNS. |
| URI | http://hdl.handle.net/20.500.11897/637100 |
| ISSN | 1662-5161 |
| DOI | 10.3389/fnhum.2021.785620 |
| Indexed | SCI(E) |
| Appears in Collections: | 北京世纪坛医院 |
