| Title | Uptake and adverse reactions of COVID-19 vaccination among people living with HIV in China: a case-control study |
| Authors | Zhao, Heping Wang, Hui Li, Hui Zheng, Weiran Yuan, Tanwei Feng, Anping Luo, Dan Hu, Yuqing Sun, Yinghui Lin, Yi-Fan Zhou, Yiguo Luo, Ganfeng Peng, Qiaoli Yang, Jianzhou Xu, Junjie Zou, Huachun |
| Affiliation | Sun Yat Sen Univ, Sch Publ Hlth Shenzhen, Shenzhen, Peoples R China Southern Univ Sci & Technol, Natl Clin Res Ctr Infect Dis, PeopleS Hosp Shenzhen 3, Shenzhen, Guangdong, Peoples R China Southern Univ Sci & Technol, Affiliated Hosp 2, Shenzhen, Guangdong, Peoples R China Shizhong Dist Ctr Dis Control & Prevent, Jinan, Peoples R China Changzhi Med Coll, Dept Prevent Med, Changzhi, Shanxi, Peoples R China Peking Univ, Peking Univ Shenzhen Hosp, Clin Res Acad, Beijing, Peoples R China Univ New South Wales, Kirby Inst, Sydney, NSW, Australia Shanghai Jiao Tong Univ, Sch Publ Hlth, Shanghai, Peoples R China |
| Issue Date | Dec-2021 |
| Publisher | HUMAN VACCINES & IMMUNOTHERAPEUTICS |
| Abstract | Objectives The coronavirus disease-2019 (COVID-19) pandemic continues to ravage the world. People living with HIV (PLHIV) are one of the most vulnerable groups. This study aims to identify the factors associated with the uptake and adverse reactions of COVID-19 vaccination. Methods We recruited PLHIV in China by convenience sampling between 7 and 23 February 2021. Participants were asked to complete an online questionnaire. Chi-squared test and multivariable logistic regression were used to assess factors associated with vaccine uptake. Results A total of 527 vaccinated and 1091 unvaccinated PLHIV were recruited. Individuals who had a higher education, engaged in occupations with a higher risk of COVID-19 infection, received influenza or pneumonia vaccine in the past 3 years (5.40, 3.36-8.77), believed in the effectiveness of vaccines (3.01, 2.20-4.12), and received media information regarding COVID-19 vaccine (2.23, 1.61-3.11), were more likely to be vaccinated. Concerning about adverse reactions (0.31, 0.22-0.44), negative impact on the progression of HIV/AIDS (0.36, 0.26-0.50) or antiretroviral therapy (ART) (0.61, 0.44-0.85), disclosure of HIV infection status (0.69, 0.49-0.96), comorbidities (0.33, 0.22-0.47), being unmarried (0.43, 0.28-0.66) and older age were negatively associated with vaccination. Of the 527 vaccinated PLHIV, 155 (29.4%) PLHIV reported adverse reactions, with pain at the injection site being the most common (18.2%). Conclusions PLHIV, who are concerned about adverse reactions, negative impact on ART outcome and disclosure of HIV infection status, were less likely to adopt COVID-19 vaccination. To increase vaccination coverage among PLHIV, health-care professionals should emphasize the benefits and necessity of vaccination and provide consultancy regarding adverse reactions. |
| URI | http://hdl.handle.net/20.500.11897/632582 |
| ISSN | 2164-5515 |
| DOI | 10.1080/21645515.2021.1991183 |
| Indexed | SCI(E) |
| Appears in Collections: | 深圳医院 |
