| Title | Could computed tomography be used as a surrogate of endoscopic ultrasonography in the screening and surveillance of small gastric Gastrointestinal stromal tumors? |
| Authors | Jia, Xiaoxuan Liu, Yiting Zhao, Jiaqi Ji, Wanying Tang, Lei Gao, Zhidong Zhang, Liming Zhang, Yinli Li, Jian Hong, Nan Wang, Yi Sun, Yingshi |
| Affiliation | Peking Univ Peoples Hosp, Dept Radiol, Beijing 100044, Peoples R China Peking Univ Canc Hosp & Inst, Dept Radiol, Key Lab Carcinogenesis & Translat Res, Minist Educ Beijing, Beijing 100142, Peoples R China Peking Univ Peoples Hosp, Dept Gastrointestinal Surg, Beijing 100044, Peoples R China Peking Univ Peoples Hosp, Dept Gastroenterol, Beijing 100044, Peoples R China Peking Univ Peoples Hosp, Dept Pathol, Beijing 100044, Peoples R China Peking Univ Canc Hosp & Inst, Dept Gastrointestinal Oncol, Key Lab Carcinogenesis & Translat Res, Minist Educ Beijing, Beijing 100142, Peoples R China |
| Issue Date | Feb-2021 |
| Publisher | EUROPEAN JOURNAL OF RADIOLOGY |
| Abstract | Purpose: To investigate whether computed tomography (CT) could be used for screening and surveillance of small gastric gastrointestinal stromal tumors (gGISTs). Method: A total of 162 pathologically confirmed small gGISTs (<= 2 cm) between September 2007 and November 2019 were retrospectively enrolled. Thirty-six lesions received contrast-enhanced CT after they were identified by endoscopy and EUS, and forty-three lesions received CT alone before surgery. The detection rate of CT for <= 1 cm gGISTs (micro-gGISTs) and 1-2 cm gGISTs (mini-gGISTs) was investigated, and the detection rate of CT alone was compared with that of CT following endoscopy and EUS. The relationship between EUS- and CT-detected high-risk features were assessed. Results: CT demonstrated a favorable detection rate for mini-gGISTs previously identified by EUS and endoscopy, whereas CT alone showed an inferior detection rate (100 % vs. 75 %, p = 0.02). CT showed a poor detection rate for micro-gGISTs, both for lesions received CT after identified by EUS and endoscopy, and those received CT alone (33.3 % vs. 14.8 %, p = 0.372). CT-detected heterogeneous enhancement pattern and presence of calcification were strongly correlated with heterogeneous echotexture (Spearman's rho=0.66, p < 0.001) and echo genic foci (Spearman's rho=0.79, p < 0.001) on EUS, respectively. CT-detected necrosis was moderately correlated with cystic spaces on EUS (Spearman's rho=0.42, p = 0.02). No correlation was found between EUSand CT-assessed irregular border. Conclusions: CT could potentially be considered as a surrogate of EUS for surveillance of mini-gGISTs instead of micro-gGISTs, whereas couldn't be used as a screening modality for either microor mini-gGISTs. |
| URI | http://hdl.handle.net/20.500.11897/622154 |
| ISSN | 0720-048X |
| DOI | 10.1016/j.ejrad.2020.109463 |
| Indexed | SCI(E) |
| Appears in Collections: | 人民医院 北京肿瘤医院 |
