| Title | CPAP increases physical activity in obstructive sleep apnea with cardiovascular disease |
| Authors | Stevens, David Loffler, Kelly A. Buman, Matthew P. Dunstan, David W. Luo, Yuanming Lorenzi-Filho, Geraldo Barbe, Ferran E. Anderson, Craig S. McEvoy, R. Doug |
| Affiliation | Flinders Univ S Australia, Coll Med & Publ Hlth, Adelaide Inst Sleep Hlth, Bedford Pk, SA, Australia Arizona State Univ, Coll Hlth Solut, Phoenix, AZ USA Baker Heart & Diabet Inst, Phys Act Lab, Melbourne, Vic, Australia Australian Catholic Univ, Mary MacKillop Inst Hlth Res, Melbourne, Vic, Australia Guangzhou Med Univ, State Key Lab Resp Dis, Affiliated Hosp 1, Guangzhou, Peoples R China Inst Coracao Incor, Sao Paulo, Brazil Hosp Univ, Sao Paulo, Brazil IRBLleida, Resp Dept, Catalonia, Spain Ctr Invest Red Enfermedades Resp CIBERES, Madrid, Spain Univ New South Wales, Fac Med, George Inst Global Hlth, Sydney, NSW, Australia Peking Univ, Hlth Sci Ctr, George Inst China, Beijing, Peoples R China Royal Prince Alfred Hosp, Neurol Dept, Sydney Hlth Partners, Sydney, NSW, Australia Southern Adelaide Local Hlth Network, Sleep & Resp Serv, Sleep Hlth Serv, Bedford Pk, SA, Australia |
| Keywords | POSITIVE AIRWAY PRESSURE QUALITY-OF-LIFE TIME EXERCISE QUESTIONNAIRE CORONARY-HEART-DISEASE DAYTIME SLEEPINESS MODERATE HEALTH TRIAL VALIDATION PREVENTION |
| Issue Date | 1-Feb-2021 |
| Publisher | JOURNAL OF CLINICAL SLEEP MEDICINE |
| Abstract | Study Objectives: Uncertainty exists over whether continuous positive airway pressure (CPAP) treatment improves moderate to vigorous physical activity levels in those with obstructive sleep apnea. We aimed to determine effects of CPAP on moderate to vigorous physical activity among participants with co-occurring cardiovascular disease and obstructive sleep apnea. Methods: The Sleep Apnea cardioVascular Endpoints (SAVE) trial recruited participants with confirmed cardiovascular disease history and obstructive sleep apnea, 45-75 years old. The 2,687 participants (1,346 randomized to CPAP plus usual care and 1,341 to usual care alone) were followed up for a mean of 3.7 years. Self-reported physical activity was recorded at baseline, 6, 24, and 48 months using the Godin-Shepard Leisure Time Exercise Questionnaire (LTEQ). We also determined effects on any limitation of physical activity reported on the physical functioning subscale of the 36-item short form questionnaire (SF-36) and proportions of participants reaching guideline recommended physical activity levels. Results: Among 2,601 participants with available data, those in the CPAP group reported significantly more physical activity compared to the usual care group, with approximately 20% higher reported moderate activities on the LTEQ during follow-up (adjusted mean 95% confidence interval) scores: 8.7, 7.5-9.9 vs 7.3, 6.1-8.5; P = .003). Those in the CPAP group also reported less limitation in physical activity (adjusted between-group difference in SF-36 physical functioning subscale score 1.66, 95% confidence interval 0.87-2.45; P< 0.001), and more reported sufficient levels of physical activity to meet recommendations. Conclusions: CPAP has positive effects on improving physical activity levels, consistent with long-term health benefits. |
| URI | http://hdl.handle.net/20.500.11897/617731 |
| ISSN | 1550-9389 |
| DOI | 10.5664/jcsm.8792 |
| Indexed | SCI(E) |
| Appears in Collections: | 医学部待认领 |
