Title Risk Factors Associated With Abnormal Urinalysis in Children
Authors Zhong, Xuhui
Ding, Jie
Wang, Zheng
Gao, Yan
Wu, Yubin
Shen, Ying
Song, Hongmei
Zhao, Zhengyan
Chen, Xinxin
Zhang, Puhong
Xu, Guobin
Yao, Chen
Zhang, Hui
Zhong, Fu
Tang, Ying
Wang, Hui
Wang, Wei
Li, Wenhao
Zhang, Wanxia
Zhu, Sainan
Shang, Meixia
Affiliation Peking Univ First Hosp, Dept Pediat, Beijing, Peoples R China
Sichuan Univ, Dept Pediat, West China Univ Hosp 2, Chengdu, Peoples R China
Guangzhou Women & Childrens Med Ctr, Dept Pediat Nephrol, Guangzhou, Peoples R China
China Med Univ, Shengjing Hosp, Dept Pediat, Shenyang, Peoples R China
Capital Med Univ, Beijing Childrens Hosp, Dept Pediat Nephrol, Beijing, Peoples R China
Peking Union Med Coll Hosp, Dept Pediat, Beijing, Peoples R China
Zhejiang Univ, Sch Med, Childrens Hosp, Dept Child Healthcare, Hangzhou, Peoples R China
Capital Med Univ, Beijing Obstet & Gynecol Hosp, Dept Infant Healthcare Sect, Beijing, Peoples R China
Peking Univ, Hlth Sci Ctr, George Inst Global Hlth, Diabet Res Program, Beijing, Peoples R China
Peking Univ First Hosp, Dept Clin Lab, Beijing, Peoples R China
Peking Univ First Hosp, Dept Biostat, Beijing, Peoples R China
Issue Date 25-Mar-2021
Publisher FRONTIERS IN PEDIATRICS
Abstract Background: Targeted urinalysis has been suggested to improve screening efficiency in adults. However, there is no well-defined target population in children yet, with limited information on the risk factors for urinalysis abnormalities. Methods: Children from infants to 17 years old were randomly selected. Dipstick urinalysis was initially performed. Among those who were abnormal, a repeat dipstick or dipstick with microscopic urinalysis was performed for confirmation. Results: In total, 70,822 children were included, with 37,866 boys and 32,956 girls. Prevalence of abnormal urinalysis was 4.3%. Age was significantly associated with abnormal urinalysis, with the highest prevalence among 12-14-year-olds. Girls were 2.0 times more likely to exhibit abnormalities. Compared with children whose guardians had a college degree or higher, those whose guardians had a high school degree or lower had a higher likelihood of abnormalities. Geographic location was also associated with abnormal results. Conclusion: Girls, children aged 12-14 years old, and children whose guardians had a low educational level and children in certain geographic locations were significantly associated with abnormal urinalysis. Identification of children at high risk would contribute to targeted urinalysis screening.
URI http://hdl.handle.net/20.500.11897/611562
ISSN 2296-2360
DOI 10.3389/fped.2021.649068
Indexed SCI(E)
Appears in Collections: 第一医院

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