Title Flexible nanosensors for non-invasive creatinine detection based on triboelectric nanogenerator and enzymatic reaction
Authors Luo, Yang
Zhao, Tianming
Dai, Yitong
Li, Qian
Fu, Hongyan
Affiliation Tsinghua Univ, Tsinghua Shenzhen Int Grad Sch, Shenzhen 518055, Guangdong, Peoples R China
Northeast Normal Univ, Coll Chem, Changchun 130024, Peoples R China
Nanjing Univ, Coll Phys, Nanjing 210046, Peoples R China
Peking Univ, Sch Elect & Comp Engn, Shenzhen 518055, Peoples R China
Issue Date 1-Apr-2021
Publisher SENSORS AND ACTUATORS A-PHYSICAL
Abstract A creatinine nanosensor has been developed by PANI (polyaniline) and PDMS (polydimethylsiloxane). The mechanism is attributed to the coupling of the triboelectric nanogenerator (TENG) and the creatinine enzymatic reaction. After enzymatic modification, the triboelectric output from PANI and PDMS carries the information of the ambient creatinine concentration, which is due to the change of PANI electroconductivity in the enzymatic reactions. The nanosensors demonstrate high sensitivity at room temperature. The response reaches 51.42 % when creatinine concentration is 10-3 mol/L. Meanwhile, its good selectivity to creatinine is demonstrated compared with NaCl, glucose, and urea. The nanosensor also supports large flexibility in bending angle measurements (10?-40?), thereby potentially allowing creatinine detection in wearable sensing applications. Experimental results show that the flexible nanosensor can offer continuous and non-invasive detection of creatinine, paving the way for electronic skin and self-powered healthcare systems. (c) 2021 Elsevier B.V. All rights reserved. Superscript/Subscript Available
URI http://hdl.handle.net/20.500.11897/610219
ISSN 0924-4247
DOI 10.1016/j.sna.2021.112585
Indexed SCI(E)
Appears in Collections: 信息工程学院

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