| Title | Nucleic Acids Analysis |
| Authors | Zhao, Yongxi Zuo, Xiaolei Li, Qian Chen, Feng Chen, Yan-Ru Deng, Jinqi Han, Da Hao, Changlong Huang, Fujian Huang, Yanyi Ke, Guoliang Kuang, Hua Li, Fan Li, Jiang Li, Min Li, Na Lin, Zhenyu Liu, Dingbin Liu, Juewen Liu, Libing Liu, Xiaoguo Lu, Chunhua Luo, Fang Mao, Xiuhai Sun, Jiashu Tang, Bo Wang, Fei Wang, Jianbin Wang, Lihua Wang, Shu Wu, Lingling Wu, Zai-Sheng Xia, Fan Xu, Chuanlai Yang, Yang Yuan, Bi-Feng Yuan, Quan Zhang, Chao Zhu, Zhi Yang, Chaoyong Zhang, Xiao-Bing Yang, Huanghao Tan, Weihong Fan, Chunhai |
| Affiliation | Xi An Jiao Tong Univ, Key Lab Biomed Informat Engn, Inst Analyt Chem & Instrument Life Sci, Minist Educ,Sch Life Sci & Technol, Xian 710049, Peoples R China Shanghai Jiao Tong Univ, Shanghai Key Lab Nucle Acid Chem & Nanomed, Sch Med, Inst Mol Med,Renji Hosp, Shanghai 200127, Peoples R China Shanghai Jiao Tong Univ, Inst Translat Med, Sch Chem & Chem Engn, Frontiers Sci Ctr Transformat Mol, Shanghai 200240, Peoples R China Fuzhou Univ, Canc Metastasis Alert & Prevent Ctr, Fujian Prov Key Lab Canc Metastasis Chemoprevent, Coll Chem,State Key Lab Photocatalysis Energy & E, Fuzhou 350108, Peoples R China Natl Ctr Nanosci & Technol, CAS Ctr Excellence Nanosci, CAS Key Lab Standardizat & Measurement Nanotechno, Beijing 100190, Peoples R China Jiangnan Univ, Sch Food Sci & Technol, State Key Lab Food Sci & Technol, Int Joint Res Lab Biointerface & Biodetect, Wuxi 214122, Jiangsu, Peoples R China China Univ Geosci, Fac Mat Sci & Chem, Engn Res Ctr Nanogeomat, Minist Educ, Wuhan 430074, Peoples R China Peking Univ, Peking Tsinghua Ctr Life Sci, Beijing Adv Innovat Ctr Genom ICG, Coll Chem & Mol Engn,Biomed Pioneering Innovat Ct, Beijing 100871, Peoples R China Hunan Univ, Coll Chem & Chem Engn, State Key Lab Chemo Biosensing & Chemometr, Changsha 410082, Peoples R China Chinese Acad Sci, Shanghai Inst Appl Phys, CAS Key Lab Interfacial Phys & Technol, Div Phys Biol, Shanghai 201800, Peoples R China Chinese Acad Sci, Shanghai Adv Res Inst, Zhangjiang Lab, Bioimaging Ctr,Shanghai Synchrotron Radiat Facil, Shanghai 201210, Peoples R China Shandong Normal Univ, Key Lab Mol & Nano Probes, Coll Chem Chem Engn & Mat Sci, Minist Educ, Jinan 250014, Peoples R China Fuzhou Univ, Fujian Prov Key Lab Anal & Detect Food Safety, Key Lab Analyt Sci Food Safety & Biol, Minist Educ,Coll Chem, Fuzhou 350116, Peoples R China Nankai Univ, State Key Lab Med Chem Biol, Res Ctr Analyt Sci, Coll Chem, Tianjin 300071, Peoples R China Nankai Univ, Tianjin Key Lab Mol Recognit & Biosensing, Tianjin 300071, Peoples R China Univ Waterloo, Waterloo Inst Nanotechnol, Dept Chem, Waterloo, ON N2L 3G1, Canada Chinese Acad Sci, Inst Chem, Lab Organ Solids, Beijing 100190, Peoples R China Univ Chinese Acad Sci, Coll Chem, Beijing 100190, Peoples R China Tsinghua Univ, Chinese Inst Brain Res CIBR, Beijing Adv Innovat Ctr Struct Biol ICSB, Sch Life Sci,Tsinghua Peking Ctr Life Sci, Beijing 100084, Peoples R China Wuhan Univ, Dept Chem, Wuhan 430072, Peoples R China Xiamen Univ, MOE Key Lab Spectrochem Anal & Instrumentat, Coll Chem & Chem Engn,Key Lab Chem Biol Fujian Pr, State Key Lab Phys Chem Solid Surfaces,Dept Chem, Xiamen 361005, Peoples R China |
| Keywords | MEDIATED-ISOTHERMAL-AMPLIFICATION ENHANCED RAMAN-SCATTERING REAL-TIME PCR LIQUID CHROMATOGRAPHY/MASS SPECTROMETRY ROLLING CIRCLE AMPLIFICATION HYBRIDIZATION-CHAIN-REACTION SEQUENCE-SPECIFIC DETECTION CIRCULATING METHYLATED DNA TANDEM REPEAT MARKERS OF-CARE DIAGNOSTICS |
| Issue Date | Dec-2020 |
| Publisher | SCIENCE CHINA-CHEMISTRY |
| Abstract | Nucleic acids are natural biopolymers of nucleotides that store, encode, transmit and express genetic information, which play central roles in diverse cellular events and diseases in living things. The analysis of nucleic acids and nucleic acids-based analysis have been widely applied in biological studies, clinical diagnosis, environmental analysis, food safety and forensic analysis. During the past decades, the field of nucleic acids analysis has been rapidly advancing with many technological breakthroughs. In this review, we focus on the methods developed for analyzing nucleic acids, nucleic acids-based analysis, device for nucleic acids analysis, and applications of nucleic acids analysis. The representative strategies for the development of new nucleic acids analysis in this field are summarized, and key advantages and possible limitations are discussed. Finally, a brief perspective on existing challenges and further research development is provided. |
| URI | http://hdl.handle.net/20.500.11897/608226 |
| ISSN | 1674-7291 |
| DOI | 10.1007/s11426-020-9864-7 |
| Indexed | SCI(E) |
| Appears in Collections: | å å¦ä¸ å å å·¥ç¨ å¦é ¢ |
