Title Acceptance of and six-month adherence to continuous positive airway pressure in patients with moderate to severe obstructive sleep apnea
Authors Luo, Kun
Zhang, Li
Zhang, Xiaolei
Han, Teng
Li, Yiming
Wang, Chen
Affiliation China Japan Friendship Hosp, Ctr Resp Med, Dept Pulm & Crit Care Med, 2 Yinghua Dongjie, Beijing 100029, Peoples R China
First Hosp Qinhuangdao, Beijing, Peoples R China
Natl Clin Res Ctr Resp Dis, Beijing, Peoples R China
Peking Univ, China Japan Friendship Sch Clin Med, Beijing, Peoples R China
Capital Med Univ, Beijing, Peoples R China
Chinese Acad Med Sci & Peking Union Med Coll, Peking Union Med Coll, Grad Sch, Beijing, Peoples R China
Keywords CHINESE PATIENTS
CPAP ACCEPTANCE
THERAPY
TITRATION
Issue Date Sep-2020
Publisher CLINICAL RESPIRATORY JOURNAL
Abstract Background Continuous positive airway pressure (CPAP) is the most effective treatment for moderate to severe obstructive sleep apnea (OSA). Acceptance of and adherence to CPAP are crucial for optimal treatment outcomes. The aim of this study was to investigate the factors influencing patients' acceptance of and adherence to CPAP treatment. Methods One hundred eighty-eight patients with moderate to severe OSA who had received CPAP titration from October 2017 to September 2018 were recruited. They were interviewed at 2 weeks and at 6 months to assess CPAP use and barriers to acceptance and adherence. Results One hundred fourteen patients (60.6%) accepted CPAP treatment. Disease severity, assessed by apnea-hypopnea index (AHI) (odds ratio [OR], 1.05; 95% confidence interval [CI], 1.01-1.08), subjective satisfaction of titration (OR, 12.83; 95% CI, 3.83-42.99), initial intention of CPAP therapy (OR, 3.33; 95% CI, 1.05-10.51) and short-term home CPAP trial (OR, 9.40; 95% CI, 2.85-31.08) were associated with acceptance of CPAP treatment. Two-third of the 98 CPAP acceptors reported good CPAP adherence at 6 months follow-up. Average hours of CPAP use per day for the first 2 weeks (OR, 1.88; 95% CI, 1.28-3.04) and the global problems associated with CPAP use (OR, 0.82; 95% CI, 0.73-0.91) were independent predictors of the six-month CPAP adherence. Conclusions Nearly 40% of patients with moderate to severe OSA did not accept CPAP treatment, and one-third of those CPAP acceptors had poor adherence to CPAP treatment. Improvement in disease awareness, comfortable titration experience, short-term home CPAP trial may be of help to increase CPAP acceptance and early experience with CPAP is important for long-term adherence. The differences in predicting factors for CPAP acceptance and adherence highlight the importance of focusing on specific aspects during the whole process management of OSA.
URI http://hdl.handle.net/20.500.11897/607710
ISSN 1752-6981
DOI 10.1111/crj.13269
Indexed SCI(E)
Appears in Collections: 中日友好医院

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