| Title | Genetically Encoded Click Chemistry(dagger) |
| Authors | Sun, Fei Zhang, Wen-Bin |
| Affiliation | Hong Kong Univ Sci & Technol, Dept Chem & Biol Engn, Kowloon, Clear Water Bay, Hong Kong, Peoples R China Peking Univ, Coll Chem & Mol Engn, Minist Educ,Ctr Soft Matter Sci & Engn, Beijing Natl Lab Mol Sci,Key Lab Polymer Chem & P, Beijing 100871, Peoples R China |
| Keywords | TOPOLOGY |
| Issue Date | May-2020 |
| Publisher | CHINESE JOURNAL OF CHEMISTRY |
| Abstract | Genetically encoded click chemistry (GECC) refers to a category of peptide/protein reactions that can spontaneously form covalent linkages with high efficiency and selectivity under mild physiological conditions. The emergence of powerful SpyTag/SpyCatcher chemistry, a prototype of GECC, has opened the door to new fields such as in cellulo protein topology engineering and design of synthetic organelles. The continuing developments of GECC will surely provide great opportunities for future materials science and synthetic biology and open up a new avenue to information-coded chemical reactions. |
| URI | http://hdl.handle.net/20.500.11897/606925 |
| ISSN | 1001-604X |
| DOI | 10.1002/cjoc.202000101 |
| Indexed | SCI(E) |
| Appears in Collections: | å å¦ä¸ å å å·¥ç¨ å¦é ¢ 高分子化学与物理教育部重点实验室 |
