| Title | Evidence-based Guideline for Therapeutic Drug Monitoring of Vancomycin: 2020 Update by the Division of Therapeutic Drug Monitoring, Chinese Pharmacological Society |
| Authors | He, Na Su, Shan Ye, Zhikang Du, Guanhua He, Bei Li, Dakui Liu, Youning Yang, Kehu Zhang, Xianglin Zhang, Yingyuan Chen, Xiao Chen, Yaolong Chen, Zhigang Dong, Yalin Du, Guang Gu, Jian Guo, Daihong Guo, Ruichen Hu, Xin Jiao, Zheng Li, Huande Liu, Gaolin Li, Zhiping Lv, Yuan Lu, Wei Miao, Liyan Qu, Jieming Sun, Tieying Tong, Rongsheng Wang, Li Wang, Minggui Wang, Rui Wen, Aidong Wu, Jiuhong Wu, Xin'an Xu, Yingchun Yang, Yong Yang, Fan Zhan, Siyan Zhang, Bikui Zhang, Chao Zhang, Huizhi Zhang, Jie Zhang, Jing Zhang, Jun Zhang, Wenting Zhao, Libo Zhao, Limei Zhao, Rongsheng Zhao, Wei Zhao, Zhigang Zhou, Wei Zeng, Xian-Tao Zhai, Suodi |
| Affiliation | Peking Univ Third Hosp, Dept Pharm, 49 Huayuan North Rd, Beijing 100191, Peoples R China Peking Univ, Sch Pharmaceut Sci, Beijing, Peoples R China McMaster Univ, Dept Hlth Res Methods Evidence & Impact, Hamilton, ON, Canada Chinese Acad Med Sci & Peking Union Med Coll, Inst Mat Med, Beijing, Peoples R China Peking Univ Third Hosp, Dept Resp Med, Beijing, Peoples R China Peking Union Med Coll Hosp, Dept Pharm, Beijing, Peoples R China Chinese Peoples Liberat Army Gen Hosp, Dept Resp & Crit Care Med, Beijing, Peoples R China Lanzhou Univ, Evidence Based Med Ctr, Sch Basic Med Sci, Lanzhou, Peoples R China Chinese GRADE Ctr, Lanzhou, Peoples R China China Japan Friendship Hosp, Dept Pharm, Beijing, Peoples R China Fudan Univ, Huashan Hosp, Inst Antibiot, Shanghai, Peoples R China Sun Yat Sen Univ, Affiliated Hosp 1, Dept Pharm, Guangzhou, Peoples R China Beijing Jishuitan Hosp, Clin Trial Ctr, Beijing, Peoples R China Xi An Jiao Tong Univ, Affiliated Hosp 1, Dept Pharm, Xian, Peoples R China Huazhong Univ Sci & Technol, Tongji Hosp, Tongji Med Coll, Dept Pharm, Wuhan, Peoples R China Peking Univ Peoples Hosp, Dept Pharm, Beijing, Peoples R China Chinese Peoples Liberat Army Gen Hosp, Drug Secur Ctr, Beijing, Peoples R China Shandong Univ, Inst Clin Pharmacol, Qilu Hosp, Jinan, Peoples R China Beijing Hosp, Dept Pharm, Beijing, Peoples R China Shanghai Jiao Tong Univ, Shanghai Chest Hosp, Dept Pharm, Shanghai, Peoples R China Cent South Univ, Xiangya Hosp 2, Dept Pharm, Changsha, Peoples R China Shanghai First Peoples Hosp, Dept Pharm, Shanghai, Peoples R China Fudan Univ, Dept Pharm, Childrens Hosp, Natl Childrens Med Ctr, Shanghai, Peoples R China Peking Univ First Hosp, Inst Clin Pharmacol, Beijing, Peoples R China Soochow Univ, Dept Pharm, Affiliated Hosp 1, Suzhou, Peoples R China Shanghai Jiao Tong Univ, Ruijin Hosp, Sch Med, Dept Resp & Crit Care Med, Shanghai, Peoples R China Beijing Hosp, Natl Ctr Gerontol, Dept Resp & Crit Care Med, Beijing, Peoples R China Sichuan Prov Peoples Hosp, Dept Pharm, Chengdu, Peoples R China Peking Univ First Hosp, Dept Pediat, Beijing, Peoples R China Chinese Peoples Liberat Army Gen Hosp, Lab Clin Pharmacol, Beijing, Peoples R China Xijing Hosp, Dept Pharm, Xian, Peoples R China Peoples Liberat Army, Dept Pharm, Hosp 306, Beijing, Peoples R China Lanzhou Univ, Dept Pharm, Hosp 1, Lanzhou, Peoples R China Chinese Acad Med Sci, Peking Union Med Coll Hosp, Dept Lab Med, Beijing, Peoples R China Peking Univ Third Hosp, Ctr Clin Epidemiol, Beijing, Peoples R China Beijing Tongren Hosp, Dept Pharm, Beijing, Peoples R China Peking Univ Third Hosp, Nursing Dept, Beijing, Peoples R China Peking Univ Third Hosp, Dept Lab Med, Beijing, Peoples R China Kunming Med Univ, Pharm Dept, Affiliated Hosp 1, Kunming, Yunnan, Peoples R China Capital Med Univ, Beijing Childrens Hosp, Dept Pharm, Beijing, Peoples R China China Med Univ, Dept Pharm, Shengjing Hosp, Shenyang, Peoples R China Shandong Univ, Cheeloo Coll Med, Sch Pharmaceut Sci, Dept Clin Pharm, Jinan, Peoples R China Beijing Tiantan Hosp, Pharm Dept, Beijing, Peoples R China Peking Univ Third Hosp, Dept Pediat, Beijing, Peoples R China Wuhan Univ, Ctr Evidence Based & Translat Med, Zhongnan Hosp, Wuhan, Peoples R China |
| Keywords | CONSENSUS TRIAL GRADE CARE |
| Issue Date | 15-Nov-2020 |
| Publisher | CLINICAL INFECTIOUS DISEASES |
| Abstract | Background. Clinical practice guidelines or recommendations often require timely and regular updating as new evidence emerges, because this can alter the risk-benefit trade-off. The scientific process of developing and updating guidelines accompanied by adequate implementation can improve outcomes. To promote better management of patients receiving vancomycin therapy, we updated the guideline for the therapeutic drug monitoring (TDM) of vancomycin published in 2015. Methods. Our updated recommendations complied with standards for developing trustworthy guidelines, including timeliness and rigor of the updating process, as well as the use of the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach. We also followed the methodology handbook published by the National Institute for Health and Clinical Excellence and the Spanish National Health System. Results. We partially updated the 2015 guideline. Apart from adults, the updated guideline also focuses on pediatric patients and neonates requiring intravenous vancomycin therapy. The guideline recommendations involve a broadened range of patients requiring TDM, modified index of TDM (both 24-hour area under the curve and trough concentration), addition regarding the necessity and timing of repeated TDM, and initial dose for specific subpopulations. Overall, 1 recommendation was deleted and 3 recommendations were modified. Eleven new recommendations were added, and no recommendation was made for 2 clinical questions. Conclusions. We updated an evidence-based guideline regarding the TDM of vancomycin using a rigorous and multidisciplinary approach. The updated guideline provides more comprehensive recommendations to inform rational and optimized vancomycin use and is thus of greater applicability. |
| URI | http://hdl.handle.net/20.500.11897/603231 |
| ISSN | 1058-4838 |
| DOI | 10.1093/cid/ciaa1536 |
| Indexed | SCI(E) |
| Appears in Collections: | 第三医院 药学院 人民医院 第一医院 |
