| Title | Acute Myelitis, Recurrent Optic Neuritis, and Seizures Over 17 Years |
| Authors | Zhao, Chen Li, Aijun Liu, Lei Wang, Jiawei Fan, Dongsheng |
| Affiliation | Peking Univ Third Hosp, Dept Neurol, Beijing, Peoples R China Peking Univ Third Hosp, Dept Ophthalmol, Beijing, Peoples R China Peking Univ Third Hosp, Beijing Key Lab Restorat Damaged Ocular Nerve, Beijing, Peoples R China Capital Med Univ, Beijing Tongren Hosp, Dept Neurol, Beijing, Peoples R China Peking Univ, Key Lab Neurosci, Minist Educ, Natl Hlth Commiss, Beijing, Peoples R China |
| Keywords | ASTROCYTOPATHY |
| Issue Date | 13-Nov-2020 |
| Publisher | FRONTIERS IN NEUROLOGY |
| Abstract | Recent discovery of several autoantibodies, such as aquaporin-4 immunoglobulin G antibodies (AQP4-IgG), myelin oligodendrocyte glycoprotein immunoglobulin G antibodies (MOG-IgG) and glial fibrillary acidic protein immunoglobulin G antibodies (GFAP-IgG), has greatly facilitated differential diagnosis of autoimmune disorders of the central nervous system. Here we report an interesting case with a history as long as 17 years. Only until she was tested positive for MOG-IgG that her diagnosis was revised from multiple sclerosis to MOG-associated disease (MOGAD). Our case illustrates the significance of screening autoantibodies in patients suspected of inflammatory autoimmune neurologic disorders. In addition, this case demonstrates how MOGAD manifests and develops in a patient over a decade. |
| URI | http://hdl.handle.net/20.500.11897/599714 |
| ISSN | 1664-2295 |
| DOI | 10.3389/fneur.2020.541146 |
| Indexed | SCI(E) |
| Appears in Collections: | 第三医院 |
