| Title | Short- and long-term outcomes of rectal cancer patients with high or improved low ligation of the inferior mesenteric artery |
| Authors | Zhang, Chenghai Chen, Lei Cui, Ming Xing, Jiadi Yang, Hong Yao, Zhendan Zhang, Nan Tan, Fei Liu, Maoxing Xu, Kai Su, Xiangqian |
| Affiliation | Peking Univ, Key Lab Carcinogenesis & Translat Res, Dept Gastrointestinal Surg 4, Minist Educ,Canc Hosp & Inst, 52 Fu Cheng Rd, Beijing 100142, Peoples R China |
| Keywords | RANDOMIZED CLINICAL-TRIAL ANTERIOR RESECTION SIGMOID COLON COLORECTAL-CANCER LOW TIE ANASTOMOTIC LEAKAGE BLOOD-FLOW SURGERY PRESERVATION METAANALYSIS |
| Issue Date | 18-Sep-2020 |
| Publisher | SCIENTIFIC REPORTS |
| Abstract | The ligation site of the inferior mesenteric artery (IMA) during laparoscopic radical resection for rectal cancer has been controversial. Consecutive patients (n=205) with rectal cancer who underwent laparoscopic-assisted low anterior resection from January 2009 to December 2015 were retrospectively analyzed. The patients were divided into high ligation (n=126) and improved low ligation groups (n=79). A total of 205 rectal cancer patients underwent laparoscopic assisted anterior resection: 126 patients in the high ligation group and 79 patients in the improved low ligation group. The improved low ligation group was better than the high ligation group in terms of postoperative flatus time and postoperative defecation time. There were no differences between the groups in terms of blood loss, operation time, total number of lymph nodes, anastomotic leakage, postoperative time to first liquid diet and postoperative hospital stay. There were also no differences in 5-year overall survival (OS). Compared to high ligation, the improved low ligation ensures the extent of lymph node dissection, and promotes the early recovery of postoperative gastrointestinal function, but does not increase the operation time, bleeding risk, or anastomotic leakage. A ligation site of the IMA in laparoscopic rectal cancer surgery may not influence oncological outcomes. |
| URI | http://hdl.handle.net/20.500.11897/592321 |
| ISSN | 2045-2322 |
| DOI | 10.1038/s41598-020-72303-0 |
| Indexed | SCI(E) |
| Appears in Collections: | 北京肿瘤医院 |
