| Title | Identifying critically important vascular access outcomes for trials in haemodialysis: an international survey with patients, caregivers and health professionals |
| Authors | Viecelli, Andrea K. Howell, Martin Tong, Allison Teixeira-Pinto, Armando O'Lone, Emma Ju, Angela Craig, Jonathan C. Hooi, Lai-Seong Lee, Timmy Lok, Charmaine E. Polkinghorne, Kevan R. Quinn, Robert R. Vachharajani, Tushar J. Vanholder, Raymond Zuo, Li Tordoir, Jan Pecoits-Filho, Roberto Yuo, Theodore Kopperschmidt, Pascal Smith, Rob Irish, Ashley B. Mori, Trevor A. Pascoe, Elaine M. Johnson, David W. Hawley, Carmel M. |
| Affiliation | Princess Alexandra Hosp, Dept Nephrol, Brisbane, Qld, Australia Univ Queensland, Ctr Hlth Serv Res, Australasian Kidney Trials Network, Brisbane, Qld, Australia Univ Sydney, Sydney Sch Publ Hlth, Sydney, NSW, Australia Childrens Hosp Westmead, Ctr Kidney Res, Sydney, NSW, Australia Flinders Univ S Australia, Coll Med & Publ Hlth, Adelaide, SA, Australia Hosp Sultanah Aminah, Dept Med, Johor Baharu, Malaysia Hosp Sultanah Aminah, Haemodialysis Unit, Johor Baharu, Malaysia Univ Alabama Birmingham, Dept Med, Birmingham, AL 35294 USA Univ Alabama Birmingham, Div Nephrol, Birmingham, AL USA Vet Affairs Med Ctr, Sect Nephrol, Birmingham, AL USA Univ Hlth Network, Div Nephrol, Toronto, ON, Canada Univ Toronto, Dept Med, Toronto, ON, Canada Monash Med Ctr, Dept Nephrol, Melbourne, Vic, Australia Monash Univ, Dept Med, Melbourne, Vic, Australia Monash Univ, Sch Publ Hlth & Prevent Med, Melbourne, Vic, Australia Univ Calgary, Dept Med, Calgary, AB, Canada Univ Calgary, Dept Community Hlth Sci, Calgary, AB, Canada Cleveland Clin Fdn, Dept Nephrol & Hypertens, Glickman Urol & Kidney Inst, 9500 Euclid Ave, Cleveland, OH 44195 USA Univ Ghent, Fac Med & Hlth Sci, Ghent, Belgium Ghent Univ Hosp, Dept Nephrol, Ghent, Belgium Peking Univ, Dept Nephrol, Peoples Hosp, Beijing, Peoples R China Univ Hosp Maastricht, Dept Surg, Maastricht, Netherlands Pontificia Univ Catolica Parana, Sch Med, Curitiba, Parana, Brazil Univ Pittsburgh, Sch Med, Dept Surg, Div Vasc Surg, Pittsburgh, PA USA Global Res & Dev, Fresenius Med Care, Schweinfurt, Germany Nightcliff Renal Unit, Darwin, NT, Australia Fiona Stanley Hosp, Dept Nephrol, Perth, WA, Australia Univ Western Australia, Med Sch, Perth, WA, Australia Translat Res Inst, Brisbane, Qld, Australia |
| Keywords | CATHETER-RELATED INFECTION BUTTONHOLE CANNULATION ARTERIOVENOUS-FISTULA PERSPECTIVES COMPLICATIONS QUESTIONNAIRE SATISFACTION MAINTENANCE SEPTICEMIA DISEASE |
| Issue Date | Apr-2020 |
| Publisher | NEPHROLOGY DIALYSIS TRANSPLANTATION |
| Abstract | Background. Vascular access outcomes reported across haemodialysis (HD) trials are numerous, heterogeneous and not always relevant to patients and clinicians. This study aimed to identify critically important vascular access outcomes. Method. Outcomes derived from a systematic review, multi-disciplinary expert panel and patient input were included in a multilanguage online survey. Participants rated the absolute importance of outcomes using a 9-point Likert scale (7-9 being critically important). The relative importance was determined by a best-worst scale using multinomial logistic regression. Open text responses were analysed thematically. Results. The survey was completed by 873 participants [224 (26%) patients/caregivers and 649 (74%) health professionals] from 58 countries. Vascular access function was considered the most important outcome (mean score 7.8 for patients and caregivers/8.5 for health professionals, with 85%/95% rating it critically important, and top ranked on best-worst scale), followed by infection (mean 7.4/8.2, 79%/92% rating it critically important, second rank on best-worst scale). Health professionals rated all outcomes of equal or higher importance than patients/caregivers, except for aneurysms. We identified six themes: necessity for HD, applicability across vascular access types, frequency and severity of debilitation, minimizing the risk of hospitalization and death, optimizing technical competence and adherence to best practice and direct impact on appearance and lifestyle. Conclusions. Vascular access function was the most critically important outcome among patients/caregivers and health professionals. Consistent reporting of this outcome across trials in HD will strengthen their value in supporting vascular access practice and shared decision making in patients requiring HD. |
| URI | http://hdl.handle.net/20.500.11897/589401 |
| ISSN | 0931-0509 |
| DOI | 10.1093/ndt/gfz148 |
| Indexed | SCI(E) |
| Appears in Collections: | 人民医院 |
