| Title | Prolonged preoperative fasting and prognosis in critically ill gastrointestinal surgery patients |
| Authors | Zhou, Gang Zhu, Fengxue An, Youzhong Qin, Lixia Lv, Jie Zhao, Xiujuan Shen, Jiawei |
| Affiliation | Peking Univ, Dept Crit Care Med, Peoples Hosp, Beijing, Peoples R China Peking Univ, Trauma Ctr, Peoples Hosp, Beijing, Peoples R China Tsinghua Univ Hosp, Dept Hlth Care, Beijing, Peoples R China |
| Keywords | INTENSIVE INSULIN THERAPY SURGICAL-PATIENTS TIGHT JUNCTIONS TIME CARBOHYDRATE COMPLICATIONS PROTECTS STAY |
| Issue Date | Mar-2020 |
| Publisher | ASIA PACIFIC JOURNAL OF CLINICAL NUTRITION |
| Abstract | Background and Objectives: This study aimed to assess the influence of prolonged preoperative fasting on prognosis in elective surgery. Methods and Study Design: A retrospective, controlled study involving patients admitted to our surgical intensive care unit who underwent a gastrointestinal operation under general anesthesia. Patients were divided into regular preoperative fasting time (n=57) and prolonged preoperative fasting time (n=73) groups. Clinical data were collected including patients' demographics, intraoperative and postoperative operation time, volume of blood loss, intensive care unit stay, hospital stay, postoperative complications and other factors. Results: Patients in the regular preoperative fasting time group had less duration of mechanical ventilation support after surgery [245 (177, 450) min vs 315 (210, 812) min (p=0.021)] and the postoperative myocardial injuries (myocardial injury 2 cases vs 11 cases, p=0.038) and reoperation percentages (reoperation 0 cases vs 7 cases, p=0.044) were lower compared to the prolonged preoperative fasting time group. In addition, patients in the regular preoperative fasting time group presented with a significantly shorter period of postoperative fasting time [6.0 (5.0, 8.0) vs 8.0 (6.0, 13.0), p=0.005]. Conclusions: Prolonged preoperative fasting time led to unfavorable outcomes after gastrointestinal operations. Thus, reducing preoperative fasting time is likely to accelerate postoperative recovery in gastrointestinal surgery patients. |
| URI | http://hdl.handle.net/20.500.11897/587628 |
| ISSN | 0964-7058 |
| DOI | 10.6133/apjcn.202003_29(1).0006 |
| Indexed | SCI(E) |
| Appears in Collections: | 人民医院 |
