| Title | HEMODYNAMICS OF CAROTID ARTERY BIFURCATION BETWEEN HEALTHY AND STENOSED MODEL BASED ON HUMAN MODEL |
| Authors | Hu, Mingcheng Guo, Jenxing Sun, Yanbin Fan, Tingting Zhao, Dongliang Chen, Guangxin |
| Affiliation | Mudanjiang Med Univ, Hongqi Hosp, Dept Radiol, Mudanjiang, Peoples R China Mudanjiang Med Univ, Outpatient Dept 1, Hongqi Hosp, Mudanjiang, Peoples R China Mudanjiang Med Univ, Med Coll, Mudanjiang, Peoples R China Peking Univ, Coll Engn, State Key Lab Turbulence & Complex Syst, Beijing, Peoples R China Capital Med Univ Beijing, Sch Biomed Engn, Beijing, Peoples R China Peking Univ, Dept Mech & Engn Sci, Beijing, Peoples R China Mudanjiang Med Univ, Med Image Coll, Mudanjiang, Peoples R China |
| Keywords | SHEAR-STRESS GEOMETRY FLOW |
| Issue Date | 2020 |
| Publisher | ACTA MEDICA MEDITERRANEA |
| Abstract | Objective: The carotid artery plays an important role in transporting the blood to the brain, and the atherosclerosis is a common disease to develop the stenosed carotid artery. Local hemodynamics are an important factor in atherosclerosis, from the development of early lesions, to the assessment of stroke risk, to determining the ultimate fate of a mature plaque. Methods: To evaluate the stenosed carotid artery, the computational fluid dynamics (CFD) method can been used to get TAWSS, OSI, and TAW SSG . We hypothesize that hemodynamic patterns are determined by the interplay of carotid artery geometry, anastomotic configuration, and severity of native coronary artery stenosis, which are strongly affected by the postoperative time. A 3D finite volume method with the inlet velocity wave and outlet resistance boundary conditions was used to compute the distribution of pressure and flow. The healthy and the stenosed patient carotid arteries have been used for our simulation. Results: The major findings are reported as: 1) smaller diameter and big stenosis rate in the stenosed model. 2) the stenosed carotid arteries has the lower WSS and higher OSI compared the healthy carotid arteries. Conclusion: Local hemodynamics are an important factor in atherosclerosis, from the development of early lesions, to the assessment of stroke risk, to determining the ultimate fate of a mature plaque. |
| URI | http://hdl.handle.net/20.500.11897/585676 |
| ISSN | 0393-6384 |
| DOI | 10.19193/0393-6384_2020_1_109 |
| Indexed | SCI(E) Scopus |
| Appears in Collections: | 工学院 湍流与复杂系统国家重点实验室 |
