| Title | Radiological exploration on adjacent segments after total cervical disc replacement with Prodisc-C prosthesis |
| Authors | Xu, Shuai Liang, Yan Meng, Fanqi Wang, Kaifeng Liu, Haiying |
| Affiliation | Peking Univ, Peoples Hosp, Dept Spinal Surg, 11 Xizhimen South St, Beijing 100044, Peoples R China |
| Keywords | Total cervical disc replacement Adjacent segments Range of motion Lordosis Intervertebral disc height |
| Issue Date | 2019 |
| Publisher | JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH |
| Abstract | PurposeThe relationship between upper or lower adjacent segments (UAS/LAS) and the cervical spine parameters was not clear yet. So, the purpose was to analyze range of motion (ROM), lordosis (LOR), and intervertebral disc height (IDH) of UAS and LAS before and after total cervical disc replacement (TDR) and to explore the influencing factors of cervical spine radiological parameters on adjacent segments.MethodsA single-center retrospective study was performed on patients completing 10-year follow-up undergone TDR. As the primary outcomes, radiological parameters included UAS-ROM/LAS-ROM, UAS-LOR/LAS-LOR, and UAS-IDH/LAS-IDH. The secondary outcomes were ROM and LOR of C2-C7 and surgical levels, IDH of surgical segments, prosthesis migration, subsidence, heterotopic ossification (HO), and adjacent segment degeneration (ASD), which were measured on X-ray.ResultsUAS-ROM and LAS-ROM remained stable in follow-up periods. There was no significance on UAS-LOR or LAS-LOR between pre- and post- operation, so was UAS-IDH or LAS-IDH. UAS-ROM was larger in the segments with ASD (P < 0.001), the same to LAS-ROM (P < 0.001), and UAS-LOR was larger in segments with ASD (P = 0.02). UAS-ROM was positively correlated with C2-C7 ROM and LOR (both P < 0.001). UAS-LOR was correlated with operated-segmental LOR while LAS-LOR were in correlation with surgical segment ROM. The influencing factors of UAS-ROM were the surgical segment ROM and C2-C7 LOR. The influencing factors of UAS-LOR and LAS-LOR were LAS-ROM and UAS-ROM, respectively. The influencing factors of UAS-IDH were LAS-IDH, surgical segment IDH, and HO while that of LAS-IDH were UAS-IDH and surgical segment IDH.ConclusionsTDR has only a little effect on the adjacent segments. There is an interaction between UAS and LAS. The maintenance on surgical segments ROM and reconstruction of IDH will benefit to adjacent segments. |
| URI | http://hdl.handle.net/20.500.11897/548128 |
| ISSN | 1749-799X |
| DOI | 10.1186/s13018-019-1194-x |
| Indexed | SCI(E) |
| Appears in Collections: | 人民医院 |
