| Title | Clinical analysis of bone metastasis of gastric cancer: incidence, clinicopathological features and survival |
| Authors | Wen, Lei Li, Yi-Ze Zhang, Jing Zhou, Cheng Yang, Hai-Nan Chen, Xin-Zu Xu, Long-Wen Kong, Sheng-Nan Wang, Xiao-Wen Zhang, Hong-Mei |
| Affiliation | Fourth Mil Med Univ, Xijing Hosp, Dept Clin Oncol, Xian, Shaanxi, Peoples R China Sanjiu Brain Hosp, Dept Oncol, Guangzhou, Guangdong, Peoples R China Peking Univ, Sch Clin Med 9, Dept Med Oncol, Beijing 100038, Peoples R China Sichuan Univ, West China Hosp, Dept Gastrointestinal Surg, Chengdu, Sichuan, Peoples R China Peking Univ, Dept Renal Canc Melanoma, Canc Hosp, Beijing, Peoples R China |
| Keywords | bone metastasis gastric cancer incidence |
| Issue Date | 2019 |
| Publisher | FUTURE ONCOLOGY |
| Abstract | Aim: We evaluated the incidence, clinicopathological features, prognostic factors and survival of gastric cancer (GC) with bone metastasis in a single large cancer center in China. Patients & methods: Patients with bone metastasis of GC were retrospectively analyzed. Overall survival was estimated using the Kaplan-Meier method. Clinicopathological factors, which were associated with prognostic factors for survival, were evaluated. Results: The incidence of bone metastasis was 11.3% for metastatic GC patients. Median overall survival time was 6.5months. Multivariate analysis revealed two independent poor prognostic factors: Eastern Cooperative Oncology Group >= 2 (p=0.023) and lack of palliative chemotherapy (p=0.018). Conclusion: The incidence of bone metastasis from metastatic GC was underestimated. The prognosis of GC with bone metastasis was poor. |
| URI | http://hdl.handle.net/20.500.11897/546891 |
| ISSN | 1479-6694 |
| DOI | 10.2217/fon-2019-0039 |
| Indexed | SCI(E) EI |
| Appears in Collections: | 北京世纪坛医院 北京肿瘤医院 |
