| Title | Electrochemical Radical Borylation of Aryl Iodides |
| Authors | Hong, Junting Liu, Qianyi Li, Feng Bai, Guangcan Liu, Guoquan Li, Man Nayal, Onkar S. Fu, Xuefeng Mo, Fanyang |
| Affiliation | Peking Univ, Dept Energy & Resources Engn, Coll Engn, Beijing 100871, Peoples R China Peking Univ, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100871, Peoples R China Peking Univ, Dept Biomed Engn, Coll Engn, Beijing 100871, Peoples R China Jiangsu Weiming Environm Protect S&T Co Ltd, Jiangsu Donghai Silicon Ind S&T Innovat Ctr, 38 Guangming Rd, Lianyungang 222300, Jiangsu, Peoples R China |
| Issue Date | 2019 |
| Publisher | CHINESE JOURNAL OF CHEMISTRY |
| Abstract | Herein, we report the first electrochemical strategy for the borylation of aryl iodides via a radical pathway using current as a driving force. A mild reaction condition allows an assorted range of readily available aryl iodides to be proficiently converted into synthetically valuable arylboronic esters under transition metal catalyst-free conditions. Moreover, this method also shows good functional group tolerance. Initial control mechanistic experiments reveal the formation of aryl radical as a key intermediate and the current plays an important role in the generation of radical intermediate. |
| URI | http://hdl.handle.net/20.500.11897/543546 |
| ISSN | 1001-604X |
| DOI | 10.1002/cjoc.201900001 |
| Indexed | CCR SCI(E) EI |
| Appears in Collections: | 工学院 药学院 天然药物与仿生药物国家重点实验室 |
