| Title | Physical comorbidities in older adults receiving antidepressants in Asia |
| Authors | Zhong, Xiao-Mei Dong, Min Wang, Fei Zhang, Qinge Ungvari, Gabor S. Ng, Chee H. Chiu, Helen F. K. Si, Tian-Mei Sim, Kang Avasthi, Ajit Grover, Sandeep Chong, Mian-Yoon Chee, Kok-Yoon Kanba, Shigenobu Lee, Min-Soo Yang, Shu-Yu Udomratn, Pichet Kallivayalil, Roy A. Tanra, Andi J. Maramis, Margarita M. Shen, Winston W. Sartorius, Norman Mahendran, Rathi Tan, Chay-Hoon Shinfuku, Naotaka Xiang, Yu-Tao |
| Affiliation | Guangzhou Med Univ, Guangzhou Hui Hosp, Affiliated Brain Hosp, Dept Neurol, Guangzhou, Guangdong, Peoples R China. Univ Macau, Fac Hlth Sci, Unit Psychiat, Taipa, Macao, Peoples R China. Capital Med Univ, Beijing Anding Hosp, Natl Clin Res Ctr Mental Disorders, Beijing, Peoples R China. Capital Med Univ, Beijing Anding Hosp, Beijing Key Lab Mental Disorders, Beijing, Peoples R China. Peking Univ, Inst Mental Hlth, Hosp 6, Beijing, Peoples R China. Peking Univ, Natl Clin Res Ctr Mental Disorders, Beijing, Peoples R China. Peking Univ, Minist Hlth, Key Lab Mental Hlth, Beijing, Peoples R China. Chinese Univ Hong Kong, Dept Psychiat, Hong Kong, Hong Kong, Peoples R China. Univ Notre Dame Australia, Graylands Hosp, Perth, WA, Australia. Univ Melbourne, Dept Psychiat, Melbourne, Vic, Australia. Buangkok Green Med Pk, Inst Mental Hlth, Singapore, Singapore. Natl Univ Singapore, Dept Psychol Med, Singapore, Singapore. Natl Univ Singapore, Dept Pharmacol, Singapore, Singapore. Postgrad Inst Med Educ & Res, Dept Psychiat, Chandigarh, India. Pushpagiri Inst Med Sci, Dept Psychiat, Thiruvalla, India. Chang Gung Univ, Kaohsiung Chang Gung Mem Hosp, Kaohsiung Med Ctr, Dept Psychiat, Taipei, Taiwan. Chang Gung Univ, Sch Med, Taipei, Taiwan. Taipei Med Univ, Taipei City Hosp, Dept Pharm, Taipei, Taiwan. Taipei Med Univ, TMU Wan Fang Med Ctr, Dept Psychiat, Taipei, Taiwan. Taipei Med Univ, Sch Med, Taipei, Taiwan. Kuala Lumpur Hosp, Tunku Abdul Rahman Inst Neurosci, Dept Psychiat & Mental Hlth, Kuala Lumpur, Malaysia. Kyushu Univ, Dept Neuropsychiat, Fukuoka, Fukuoka, Japan. Kobe Univ, Sch Med, Int Ctr Med Res, Kobe, Hyogo, Japan. Korea Univ, Coll Med, Dept Psychiat, Seoul, South Korea. Prince Songkla Univ, Dept Psychiat, Fac Med, Hat Yai, Thailand. Hasanuddin Univ, Fac Med, Dept Psychiat, Makassar, Sulawesi Selata, Indonesia. Univ Airlangga, Dr Soetomo Hosp, Fac Med, Surabaya, Jawa Timur, Indonesia. Assoc Improvement Mental Hlth Programmes, Geneva, Switzerland. Univ Macau, Fac Hlth Sci, Ave Univ 3-F,Bldg E12, Taipa, Macau, Peoples R China. |
| Keywords | antidepressant Asia older adults physical comorbidity QUALITY-OF-LIFE MEDICAL COMORBIDITY BIPOLAR DISORDER BENZODIAZEPINE USE SCHIZOPHRENIA DEPRESSION DETERMINANTS ILLNESSES OUTCOMES |
| Issue Date | 2018 |
| Publisher | PSYCHOGERIATRICS |
| Citation | PSYCHOGERIATRICS. 2018, 18(5), 351-356. |
| Abstract | BackgroundThe present study explored the patterns of physical comorbidities and their associated demographic and clinical factors in older psychiatric patients prescribed with antidepressants in Asia. MethodsDemographic and clinical information of 955 older adults were extracted from the database of the Research on Asian Psychotropic Prescription Patterns for Antidepressants (REAP-AD) project. Standardized data collection procedure was used to record demographic and clinical data. ResultsProportion of physical comorbidities in this cohort was 44%. Multiple logistic regression analyses showed that older age (OR=1.7, P<0.001), higher number of depressive symptoms (OR=1.09, P=0.016), being treated in psychiatric hospital (OR=0.5, P=0.002), living in high income countries/territories (OR=2.4, P=0.002), use of benzodiazepines (OR=1.4, P=0.013) and diagnosis of other psychiatric disorders' (except mood, anxiety disorders and schizophrenia) (OR=2.7, P<0.001) were significantly associated with physical comorbidities. ConclusionsPhysical comorbidities in older patients prescribed with antidepressants were common in Asia. Integrating physical care into the treatment of older psychiatric patients should be urgently considered. |
| URI | http://hdl.handle.net/20.500.11897/517656 |
| ISSN | 1346-3500 |
| DOI | 10.1111/psyg.12327 |
| Indexed | SCI(E) PubMed |
| Appears in Collections: | 第六医院 |
