Title | Putting gold nanocages to work for optical imaging, controlled release and cancer theranostics |
Authors | Pang, Bo Yang, Xuan Xia, Younan |
Affiliation | Georgia Inst Technol, Wallace H Coulter Dept Biomed Engn, Atlanta, GA 30332 USA. Emory Univ, Atlanta, GA 30332 USA. Peking Univ, Coll Engn, Dept Biomed Engn, Beijing 100871, Peoples R China. Georgia Inst Technol, Sch Chem & Biochem, Sch Chem & Biomol Engn, Atlanta, GA 30332 USA. Georgia Inst Technol, Wallace H Coulter Dept Biomed Engn, Atlanta, GA 30332 USA. Xia, YN (reprint author), Emory Univ, Atlanta, GA 30332 USA. Xia, YN (reprint author), Georgia Inst Technol, Sch Chem & Biochem, Sch Chem & Biomol Engn, Atlanta, GA 30332 USA. |
Keywords | cancer theranostics controlled release gold nanostructures hollow nanostructures nanocages near-infrared optical imaging plasmonics POSITRON-EMISSION-TOMOGRAPHY PHASE-CHANGE MATERIALS IN-VIVO DRUG-DELIVERY AG NANOCUBES AU NANOCAGES PHOTOACOUSTIC MICROSCOPY BIOMEDICAL APPLICATIONS SILVER NANOPARTICLES PHOTOTHERMAL THERAPY |
Issue Date | 2016 |
Publisher | NANOMEDICINE |
Citation | NANOMEDICINE.2016,11(13),1715-1728. |
Abstract | Gold nanocages are hollow nanostructures with ultrathin, porous walls. They are bio-inert and their surface can be readily modified with functional groups to specifically interact with the biological system of interest. They have remarkable optical properties, including localized surface plasmon resonance peaks tunable to the near-infrared region, strong absorption and scattering, as well as two-and three-photon luminescence. With the establishment of robust protocols for both synthesis and surface functionalization, Au nanocages have been extensively explored for various biomedical applications. In this review, we begin with a brief account of the synthesis and properties of Au nanocages, and then highlight some of the recent developments in applying them to an array of biomedical applications related to optical imaging, controlled release and cancer theranostics. |
URI | http://hdl.handle.net/20.500.11897/492056 |
ISSN | 1743-5889 |
DOI | 10.2217/nnm-2016-0109 |
Indexed | SCI(E) |
Appears in Collections: | 工学院 |