| Title | Biological effect and molecular mechanism study of biomaterials based on proteomic research |
| Authors | Zhen, Zhen Zheng, Yufeng Ge, Zigang Lai, Chen Xi, Tingfei |
| Affiliation | Peking Univ, Shenzhen Inst, Shenzhen 518057, Peoples R China. Peking Univ, Coll Engn, Beijing 100871, Peoples R China. Peking Univ, Acad Adv Interdisciplinary Studies, Beijing 100871, Peoples R China. |
| Keywords | Proteomics Biomaterials Biological effect Molecular mechanism HUMAN DERMAL FIBROBLASTS GOLD NANOPARTICLES SILVER NANOPARTICLES BIOCOMPATIBILITY TITANIUM DIFFERENTIATION SCAFFOLD CELLS |
| Issue Date | 2017 |
| Publisher | JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY |
| Citation | JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY.2017,33(7),607-615. |
| Abstract | Along with the role transformation of biomaterials from bioinert substitute to regenerative inducer, the biological effect and mechanism of material-organism interaction become more important. Since most of animal tests and cellular experiments stay on the phenomenon description instead of mechanism interpretation, the development of proteomics technologies provides a golden opportunity to uncover the molecular interaction mechanism between biomaterial-organism on whole scale. This review summarizes current application of proteomics in biological effect and mechanism study of biomaterials, and discusses the development and challenges for future studies. (C) 2017 Published by Elsevier Ltd on behalf of The editorial office of Journal of Materials Science & Technology. |
| URI | http://hdl.handle.net/20.500.11897/472381 |
| ISSN | 1005-0302 |
| DOI | 10.1016/j.jmst.2017.01.001 |
| Indexed | SCI(E) 中国科学引文数据库(CSCD) |
| Appears in Collections: | 深圳研究生院待认领 工学院 前沿交叉学科研究院 |
