Title | Internal limiting membrane peeling and gas tamponade for myopic foveoschisis: a systematic review and meta-analysis |
Authors | Meng, Bo Zhao, Lu Yin, Yi Li, Hongyang Wang, Xiaolei Yang, Xiufen You, Ran Wang, Jialin Zhang, Youjing Wang, Hui Du, Ran Wang, Ningli Zhan, Siyan Wang, Yanling |
Affiliation | Capital Med Univ, Beijing Friendship Hosp, 95 Yong An Rd, Beijing 100050, Peoples R China. Capital Med Univ, Beijing Tongren Hosp, Beijing Tongren Eye Ctr, Beijing, Peoples R China. Peking Univ, Sch Publ Hlth, Hlth Sci Ctr, Dept Epidemiol & Biostat, Beijing, Peoples R China. |
Keywords | Internal limiting membrane peeling Tamponade Myopic foveoschisis Systematic review RETINAL-DETACHMENT MACULAR HOLE FOVEAL DETACHMENT VISUAL-ACUITY VITRECTOMY EYES RETINOSCHISIS PREVALENCE INJECTION TRACTION |
Issue Date | 2017 |
Publisher | BMC OPHTHALMOLOGY |
Citation | BMC OPHTHALMOLOGY.2017,17. |
Abstract | Background: Myopic foveoschisis (MF) is among the leading causes of visual loss in high myopia. However, it remains controversial whether internal limiting membrane (ILM) peeling or gas tamponade is necessary treatment option for MF. Methods: PubMed, EMBASE, CBM, CNKI, WANFANG DATA and VIP databases were systematically reviewed. Outcome indicators were myopic foveoschisis resolution rate, visual acuity improvement and postoperative complications. Results: Nine studies that included 239 eyes were selected. The proportion of resolution of foveoschisis was higher in ILM peeling group than non-ILM peeling group (OR = 2.15, 95% CI: 1.06-4.35; P = 0.03). The proportion of postoperative complications was higher in Tamponade group than non-Tamponade group (OR = 10.81, 95% CI: 1.26-93.02; P = 0.03). However, the proportion of visual acuity improvement (OR = 1.63, 95% CI: 0.56-4.80; P = 0.37) between ILM peeling group and non-ILM peeling group and the proportion of resolution of foveoschisis (OR = 1.80, 95% CI: 0.76-4.28; P = 0.18) between Tamponade group and non-Tamponade group were similar. Conclusions: Vitrectomy with internal limiting membrane peeling could contribute to better resolution of myopic foveoschisis than non-peeling, however it does not significantly influence the proportion of visual acuity improvement and postoperative complications. Vitrectomy with gas tamponade is associated with more complications than non-tamponade and does not significantly influence the proportion of visual acuity improvement and resolution of myopic foveoschisis. |
URI | http://hdl.handle.net/20.500.11897/470909 |
ISSN | 1471-2415 |
DOI | 10.1186/s12886-017-0562-8 |
Indexed | SCI(E) |
Appears in Collections: | 公共卫生学院 |