Title Internal limiting membrane peeling and gas tamponade for myopic foveoschisis: a systematic review and meta-analysis
Authors Meng, Bo
Zhao, Lu
Yin, Yi
Li, Hongyang
Wang, Xiaolei
Yang, Xiufen
You, Ran
Wang, Jialin
Zhang, Youjing
Wang, Hui
Du, Ran
Wang, Ningli
Zhan, Siyan
Wang, Yanling
Affiliation Capital Med Univ, Beijing Friendship Hosp, 95 Yong An Rd, Beijing 100050, Peoples R China.
Capital Med Univ, Beijing Tongren Hosp, Beijing Tongren Eye Ctr, Beijing, Peoples R China.
Peking Univ, Sch Publ Hlth, Hlth Sci Ctr, Dept Epidemiol & Biostat, Beijing, Peoples R China.
Keywords Internal limiting membrane peeling
Tamponade
Myopic foveoschisis
Systematic review
RETINAL-DETACHMENT
MACULAR HOLE
FOVEAL DETACHMENT
VISUAL-ACUITY
VITRECTOMY
EYES
RETINOSCHISIS
PREVALENCE
INJECTION
TRACTION
Issue Date 2017
Publisher BMC OPHTHALMOLOGY
Citation BMC OPHTHALMOLOGY.2017,17.
Abstract Background: Myopic foveoschisis (MF) is among the leading causes of visual loss in high myopia. However, it remains controversial whether internal limiting membrane (ILM) peeling or gas tamponade is necessary treatment option for MF. Methods: PubMed, EMBASE, CBM, CNKI, WANFANG DATA and VIP databases were systematically reviewed. Outcome indicators were myopic foveoschisis resolution rate, visual acuity improvement and postoperative complications. Results: Nine studies that included 239 eyes were selected. The proportion of resolution of foveoschisis was higher in ILM peeling group than non-ILM peeling group (OR = 2.15, 95% CI: 1.06-4.35; P = 0.03). The proportion of postoperative complications was higher in Tamponade group than non-Tamponade group (OR = 10.81, 95% CI: 1.26-93.02; P = 0.03). However, the proportion of visual acuity improvement (OR = 1.63, 95% CI: 0.56-4.80; P = 0.37) between ILM peeling group and non-ILM peeling group and the proportion of resolution of foveoschisis (OR = 1.80, 95% CI: 0.76-4.28; P = 0.18) between Tamponade group and non-Tamponade group were similar. Conclusions: Vitrectomy with internal limiting membrane peeling could contribute to better resolution of myopic foveoschisis than non-peeling, however it does not significantly influence the proportion of visual acuity improvement and postoperative complications. Vitrectomy with gas tamponade is associated with more complications than non-tamponade and does not significantly influence the proportion of visual acuity improvement and resolution of myopic foveoschisis.
URI http://hdl.handle.net/20.500.11897/470909
ISSN 1471-2415
DOI 10.1186/s12886-017-0562-8
Indexed SCI(E)
Appears in Collections: 公共卫生学院

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