| Title | Application of alpha-amino acids for the transition-metal-free synthesis of pyrrolo[1,2-a]quinoxalines |
| Authors | Liu, Huanhuan Zhou, Feiyu Luo, Wen Chen, Yuxin Zhang, Chenyang Ma, Chen |
| Affiliation | Shandong Univ, Sch Chem & Chem Engn, Jinan 250100, Shandong, Peoples R China. Peking Univ, State Key Lab Nat & Biomimet Drugs, Beijing 100191, Peoples R China. Shandong Univ, Sch Chem & Chem Engn, Jinan 250100, Shandong, Peoples R China. Ma, C (reprint author), Peking Univ, State Key Lab Nat & Biomimet Drugs, Beijing 100191, Peoples R China. |
| Keywords | ALIPHATIC CARBOXYLIC-ACIDS C-H FUNCTIONALIZATION IN-VITRO EVALUATION DECARBOXYLATIVE AMINATION BIOLOGICAL EVALUATION ARYL IODIDES DERIVATIVES CONSTRUCTION INHIBITORS ALCOHOLS |
| Issue Date | 2017 |
| Publisher | ORGANIC & BIOMOLECULAR CHEMISTRY |
| Citation | ORGANIC & BIOMOLECULAR CHEMISTRY.2017,15(34),7157-7164. |
| Abstract | A practical and concise protocol for the efficient synthesis of pyrrolo[1,2-a] quinoxalines from readily available a-amino acids and 2-(1H-pyrrol-1-yl) anilines under transition metal-free conditions has been established. This protocol, which includes the formation of new C-C and C-N bonds, features a wide substrate scope with a broad range of functional group tolerance. |
| URI | http://hdl.handle.net/20.500.11897/470871 |
| ISSN | 1477-0520 |
| DOI | 10.1039/c7ob01688c |
| Indexed | SCI(E) |
| Appears in Collections: | 天然药物与仿生药物国家重点实验室 |
