| Title | Animal Models for Hepatitis E Virus |
| Authors | Wang, Lin Wang, Ling |
| Affiliation | Peking Univ, Hlth Sci Ctr, Dept Microbiol, 38 Xueyuan Rd, Beijing 100191, Peoples R China. Peking Univ, Hlth Sci Ctr, Ctr Infect Dis, Sch Basic Med Sci, 38 Xueyuan Rd, Beijing 100191, Peoples R China. Peking Univ, Hlth Sci Ctr, Dept Microbiol, 38 Xueyuan Rd, Beijing 100191, Peoples R China. Wang, L (reprint author), Peking Univ, Hlth Sci Ctr, Ctr Infect Dis, Sch Basic Med Sci, 38 Xueyuan Rd, Beijing 100191, Peoples R China. |
| Keywords | HEV Animal models Pathogenesis Cross-species infection Vaccine study CROSS-SPECIES INFECTION NON-B-HEPATITIS CIS-REACTIVE ELEMENT LIVER CHIMERIC MICE TRANSMITTED NON-A HEV INFECTION RHESUS-MONKEYS E VACCINE CYNOMOLGUS MACAQUES UNITED-STATES |
| Issue Date | 2016 |
| Publisher | HEPATITIS E VIRUS |
| Citation | HEPATITIS E VIRUS.2016,948,161-173. |
| Abstract | Animal models are one of the most important tools in the study of human hepatitis E virus (HEV) infection. They are particularly important in light of the major limitations of the cell culture system for HEV. Besides nonhuman primates, which are extremely valuable because of their susceptibility to HEV genotypes 1-4, animals like swine, rabbit, and chicken are also potential models for studies of pathogenesis, cross-species infection, and the molecular biology of HEV. Identification of the most useful animal model for human HEV infection studies is crucial to further investigations into this ubiquitous yet poorly understood virus. |
| URI | http://hdl.handle.net/20.500.11897/457440 |
| ISSN | 0065-2598 |
| DOI | 10.1007/978-94-024-0942-0_9 |
| Indexed | SCI(E) PubMed |
| Appears in Collections: | 医学部待认领 |
