| Title | Dioxygen-Promoted Pd-Catalyzed Aminocarbonylation of Organoboronic Acids with Amines and CO: A Direct Approach to Tertiary Amides |
| Authors | Ren, Long Li, Xinwei Jiao, Ning |
| Affiliation | Peking Univ, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Xue Yuan Rd 38, Beijing 100191, Peoples R China. East China Normal Univ, Shanghai Key Lab Green Chem & Chem Proc, Dept Chem, Shanghai 200062, Peoples R China. Peking Univ, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Xue Yuan Rd 38, Beijing 100191, Peoples R China. Jiao, N (reprint author), East China Normal Univ, Shanghai Key Lab Green Chem & Chem Proc, Dept Chem, Shanghai 200062, Peoples R China. |
| Keywords | CARBONYLATIVE COUPLING REACTIONS N-SUBSTITUTED FORMAMIDES ALKENYL BORONIC ACIDS H BOND ACTIVATION ONE-POT ATMOSPHERIC-PRESSURE OXIDATIVE AMIDATION EFFICIENT CATALYST CARBOXYLIC-ACIDS ARYL HALIDES |
| Issue Date | 2016 |
| Publisher | ORGANIC LETTERS |
| Citation | ORGANIC LETTERS.2016,18(22),5852-5855. |
| Abstract | A direct approach from organoboronic acids and amines to tertiary amides via Pd-catalyzed aerobic aminocarbonylation has been developed. The presence of O-2 significantly promotes the efficiency of this transformation. This method uses commercially available organoboronic acids and cheap CO and O-2 (1 atm), which renders amides an easy synthesis with broad substrate scope and high functional group tolerance. |
| URI | http://hdl.handle.net/20.500.11897/457132 |
| ISSN | 1523-7060 |
| DOI | 10.1021/acs.orglett.6b02913 |
| Indexed | SCI(E) PubMed |
| Appears in Collections: | 药学院 天然药物与仿生药物国家重点实验室 |
