| Title | Magnetic resonance imaging in early rheumatoid arthritis: a multicenter, prospective study |
| Authors | Li, Ru Liu, Xia Ye, Hua Yao, Hai-Hong Guo, Jia-Long Li, Guang-Tao Li, Xing-Fu Xue, Yu Zhao, Jin-Xia Gu, Fei Zou, Qing-Hua Chen, Li-Na Bi, Li-Qi Zhang, Zhuo-Li Zou, He-Jian Liu, Xiang-Yuan Sun, Ling-Yun Fang, Yong-Fei Zhu, Ping Su, Yin Li, Zhan-Guo |
| Affiliation | Peking Univ, Peoples Hosp, Dept Rheumatol & Immunol, 11 Xizhimen South St, Beijing 100044, Peoples R China. Peking Univ, Peoples Hosp, Dept Radiol, Beijing 100871, Peoples R China. Jilin Univ, China Japan Union Hosp, Dept Rheumatol & Immunol, Changchun 130023, Peoples R China. Peking Univ, Hosp 1, Dept Rheumatol & Immunol, Beijing 100871, Peoples R China. Shandong Univ, Qilu Hosp, Dept Rheumatol & Immunol, Jinan 250100, Peoples R China. Fudan Univ, Huashan Hosp, Dept Rheumatol & Immunol, Shanghai 200433, Peoples R China. Peking Univ, Hosp 3, Dept Rheumatol & Immunol, Beijing 100871, Peoples R China. Nanjing Univ, Sch Med, Affiliated Drum Tower Hosp, Dept Rheumatol & Immunol, Nanjing 210008, Jiangsu, Peoples R China. Third Mil Med Univ, Southwest Hosp, Dept Rheumatol & Immunol, Chongqing, Peoples R China. Fourth Mil Med Univ, Xijing Hosp, Dept Clin Immunol, Xian 710032, Peoples R China. |
| Keywords | Early rheumatoid arthritis Magnetic resonance imaging Synovitis BONE-MARROW EDEMA CLASSIFICATION CRITERIA WRISTS HANDS MRI |
| Issue Date | 2016 |
| Publisher | CLINICAL RHEUMATOLOGY |
| Citation | CLINICAL RHEUMATOLOGY.2016,35,(2),303-308. |
| Abstract | To identify the magnetic resonance imaging (MRI) features of hands and wrists in early rheumatoid arthritis (RA). A total of 129 early arthritis patients (a parts per thousand currency sign1 year) were enrolled in the study. At presentation, MRI of the hands was performed, with clinical and laboratory analyses. After a 1-year follow-up, clinical diagnosis of early RA or non-RA was confirmed by two rheumatologists. The characteristics of MRI variables at baseline in RA patients not fulfilling ACR 1987 criteria [RA-87(-)] were compared with those fulfilling ACR1987 criteria [RA-87(+)] and non-RA. In the 129 early arthritis patients, 90 were diagnosed with RA in a 1-year follow-up. There were 47.8 % (43/90) of the RA patients not fulfilling ACR 1987 criteria [RA-87(-)]. The scores of synovitis in RA-87(-) patients were similar with those in RA-87(+) [Synovitis score, 14.0 (IQR, 4.0-25.0) vs. 14.0 (IQR, 10.0-25.0), p > 0.05]. Compared with those in non-RA, RA-87(-) patients had higher synovitis scores and occurrence of synovitis in proximal interphalangeal (PIP) joints [synovitis score, 14.0 (IQR, 4.0-25.0) vs. 6.0 (IQR, 2.0-14.5), p = 0.046; occurrence of PIP synovitis: 53.5 vs. 27.3 %, p = 0.02]. There was no significant difference of bone marrow edema, bone erosion, and tenosynovitis between RA-87(-) and non-RA. Synovitis in PIP joints was independent predictor for RA-87(-) [OR, 3.1 (95 %CI 1.2-8.1)]. High synovitis scores and synovitis in PIP joints on MRI were important in early RA, especially those not fulfilling ACR 1987 criteria. |
| URI | http://hdl.handle.net/20.500.11897/435346 |
| ISSN | 0770-3198 |
| DOI | 10.1007/s10067-016-3180-6 |
| Indexed | SCI(E) PubMed |
| Appears in Collections: | 人民医院 第一医院 第三医院 |
