Title Comparison of three classification criteria of rheumatoid arthritis in an inception early arthritis cohort
Authors Ye, Hua
Su, Yin
Li, Ru
Zhao, Jinxia
Liu, Xiangyuan
Mei, Yifang
Zhang, Zhiyi
Guo, Jialong
Bi, Liqi
Liu, Xia
Wang, Guochun
Liu, Jinjing
Leng, Xiaomei
Gu, Fei
Sun, Lingyun
Zou, Qinghua
Fang, Yongfei
Jiang, Quan
Li, Zhanguo
Affiliation Peking Univ, Peoples Hosp, Dept Rheumatol & Immunol, 11 Xizhimen South St, Beijing 100044, Peoples R China.
Peking Univ, Dept Rheumatol & Immunol, Hosp 3, Beijing, Peoples R China.
Harbin Med Univ, Affiliated Hosp 1, Dept Rheumatol & Immunol, Harbin, Peoples R China.
Jilin Univ, China Japan Union Hosp, Dept Rheumatol & Immunol, Changchun, Peoples R China.
China Japan Friendship Hosp, Dept Rheumatol & Immunol, Beijing, Peoples R China.
Beijing Union Med Coll Hosp, Dept Rheumatol & Immunol, Beijing, Peoples R China.
Nanjing Univ, Affiliated Drum Tower Hosp, Dept Rheumatol & Immunol, Nanjing, Jiangsu, Peoples R China.
Third Mil Med Univ, Southwest Hosp, Dept Rheumatol & Immunol, Chongqing, Peoples R China.
Acad Tradit Chinese Med, Guang An Men Hosp, Beijing, Peoples R China.
Keywords Arthritis
Classification criteria
Early
Rheumatoid
2010 ACR/EULAR CRITERIA
1987 ACR CRITERIA
AMERICAN-COLLEGE
RHEUMATOLOGY/EUROPEAN LEAGUE
INFLAMMATORY POLYARTHRITIS
PERFORMANCE
Issue Date 2016
Publisher CLINICAL RHEUMATOLOGY
Citation CLINICAL RHEUMATOLOGY.2016,35(10),2397-2401.
Abstract The aim of this study is to compare the three classification criteria for rheumatoid arthritis (RA) in a large cohort of early arthritis patients. Patients who had at least one clinically swollen joint with disease duration no more than 1 year and age more than 18 years were enrolled. The clinical and laboratory parameters were recorded. The patients were diagnosed by two experienced rheumatologists. Undiagnosed patients were followed up every 3 months until 1 year. The sensitivity, specificity, and predictive value were compared among the early RA (ERA) criteria, the 1987 ACR criteria, and the 2010 ACR/EULAR criteria in this inception cohort of early arthritis patients. A total of 417 patients with inflammatory arthritis were recruited. By the end of 1 year follow-up, there were 399 patients (95.7 %) with a definitive diagnosis and 18 (4.3 %) patients remained as undifferentiated arthritis. Among the patients with definitive diagnosis, 202 (50.6 %) patients were diagnosed with RA and 197 (49.4 %) with non-RA. The sensitivity of ERA criteria was equal to 2010 ACR/EULAR criteria (both were 72.3 %), but much higher than 1987 ACR criteria (72.3 vs. 39.1 %, P < 0.001); the specificity of ERA criteria was comparable to 2010 ACR/EULAR criteria (87.8 vs. 83.2 %) and slightly lower than 1987 ACR criteria (87.8 vs. 92.4 %, P < 0.001). Unlike the complicated scoring system of 2010 criteria, the ERA criteria were more feasible to use in practice with five criteria only. The ERA criteria have a high sensitivity and more clinically feasibility in daily practice for early RA diagnosis.
URI http://hdl.handle.net/20.500.11897/433906
ISSN 0770-3198
DOI 10.1007/s10067-016-3281-2
Indexed SCI(E)
PubMed
Appears in Collections: 人民医院
第三医院

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