| Title | Synthesis of 2,3-Disubstituted Indoles and Benzofurans by the Tandem Reaction of Rhodium(II)-Catalyzed Intramolecular C-H Insertion and Oxygen-Mediated Oxidation |
| Authors | Shen, Hongjuan Fu, Junkai Yuan, Hao Gong, Jianxian Yang, Zhen |
| Affiliation | Peking Univ, Shenzhen Grad Sch, Sch Chem Biol & Biotechnol, Lab Chem Genom, Shenzhen 518055, Peoples R China. |
| Keywords | AZAVINYL CARBENES TERMINAL ALKYNES EFFICIENT SYNTHESIS INTERNAL ALKYNES FACILE SYNTHESIS 1,2,3-TRIAZOLES HETEROCYCLES ANNULATION BOND N-SULFONYL-1,2,3-TRIAZOLES |
| Issue Date | 2016 |
| Publisher | JOURNAL OF ORGANIC CHEMISTRY |
| Citation | JOURNAL OF ORGANIC CHEMISTRY.2016,81(21),10180-10192. |
| Abstract | A highly effective and straightforward method to construct a wide range of functionalized 2,3-disubstituted indoles has been developed. The method involves the tandem reaction of rhodium(II)-catalyzed denitrogenative annulation of triazole-based benzyl anilines and oxygen-mediated oxidative aromatization. The developed method can also be used to synthesize 2,3-disubstituted benzofurans by replacing the benzyl anilines with benzyl phenols. |
| URI | http://hdl.handle.net/20.500.11897/433762 |
| ISSN | 0022-3263 |
| DOI | 10.1021/acs.joc.6b00611 |
| Indexed | SCI(E) PubMed |
| Appears in Collections: | 化学生物学与生物技术学院 |
