| Title | Anti-neuroinflammatory constituents from Artemisia argyi |
| Authors | Wang Shu Jiang Yong Zeng Kewu Cui Jingrong Tu Pengfei |
| Affiliation | Peking University Health Science Center |
| Keywords | Artemisia argyi Asteraceae Chemical constituents Anti-neuroinflammatory |
| Issue Date | 2013 |
| Publisher | Journal of Chinese Pharmaceutical Sciences |
| Citation | Journal of Chinese Pharmaceutical Sciences.2013,22(4),377-380. |
| Abstract | Chemical constituents of the leaves of Artemisia argyi were investigated. By using a variety of chromatographic techniques and spectroscopic methods, six compounds were isolated and identified as follows: clemaphenol A (1), aurantiamide acetate (2), camelliagenin A (3), japonica acid (4), labd-13(E)-ene-8a, 15-diol (5), and 3p-acetoxy-20-oxo-21-nordammaran-23-oic acid (6). Among these products, compounds 1 and 3-6 were obtained from the genus Artemisia for the first time and compound 2 was firstly reported from the species. Additionally, compound 5 displayed an inhibitory effect against the lipopolysaccharide (LPS)-induced nitric oxide (NO) production in BV-2 microglial cells with an IC_(50) value of 6.68 μM. |
| URI | http://hdl.handle.net/20.500.11897/417974 |
| Indexed | 中国科技核心期刊(ISTIC) 中国科学引文数据库(CSCD) |
| Appears in Collections: | 医学部待认领 |
