| Title | The Experimental Teaching Reform in Biochemistry and Molecular Biology for Undergraduate Students in Peking University Health Science Center |
| Authors | Yang, Xiaohan Sun, Luyang Zhao, Ying Yi, Xia Zhu, Bin Wang, Pu Lin, Hong Ni, Juhua |
| Affiliation | Peking Univ, Hlth Sci Ctr, Dept Biochem & Mol Biol, Beijing 100191, Peoples R China. Peking Univ, Hlth Sci Ctr, Dept Biochem & Mol Biol, 38 Xue Yuan Rd, Beijing 100191, Peoples R China. |
| Keywords | experimental teaching reform project-oriented experiment Western blotting DNA ladder assay APOPTOSIS PROTEINS |
| Issue Date | 2015 |
| Publisher | BIOCHEMISTRY AND MOLECULAR BIOLOGY EDUCATION |
| Citation | BIOCHEMISTRY AND MOLECULAR BIOLOGY EDUCATION.2015,43,(6),428-433. |
| Abstract | Since 2010, second-year undergraduate students of an eight-year training program leading to a Doctor of Medicine degree or Doctor of Philosophy degree in Peking University Health Science Center (PKUHSC) have been required to enter the "Innovative talent training project." During that time, the students joined a research lab and participated in some original research work. There is a critical educational need to prepare these students for the increasing accessibility of research experience. The redesigned experimental curriculum of biochemistry and molecular biology was developed to fulfill such a requirement, which keeps two original biochemistry experiments (Gel filtration and Enzyme kinetics) and adds a new two-experiment component called "Analysis of antitumor drug induced apoptosis." The additional component, also known as the "project-oriented experiment" or the "comprehensive experiment," consists of Western blotting and a DNA laddering assay to assess the effects of etoposide (VP16) on the apoptosis signaling pathways. This reformed laboratory teaching system aims to enhance the participating students overall understanding of important biological research techniques and the instrumentation involved, and to foster a better understanding of the research process all within a classroom setting. Student feedback indicated that the updated curriculum helped them improve their operational and self-learning capability, and helped to increase their understanding of theoretical knowledge and actual research processes, which laid the groundwork for their future research work. (C) 2015 by The International Union of Biochemistry and Molecular Biology, 43: 428-433, 2015. |
| URI | http://hdl.handle.net/20.500.11897/417645 |
| ISSN | 1470-8175 |
| DOI | 10.1002/bmb.20890 |
| Indexed | SCI(E) PubMed |
| Appears in Collections: | 医学部待认领 |
