| Title | Natural variation of H3K27me3 modification in two Arabidopsis accessions and their hybrid |
| Authors | Yang, Mei Wang, Xuncheng Huang, Hao Ren, Diqiu Su, Yan'e Zhu, Pan Zhu, Danmeng Fan, Liumin Chen, Liangbi He, Guangming Deng, Xing Wang |
| Affiliation | Peking Univ, Sch Adv Agr Sci, Peking Tsinghua Ctr Life Sci, State Key Lab Prot & Plant Gene Res, Beijing 100871, Peoples R China. Peking Univ, Sch Life Sci, Beijing 100871, Peoples R China. Tsinghua Univ, Sch Life Sci, Tsinghua Peking Joint Ctr Life Sci, Beijing 100084, Peoples R China. Hunan Normal Univ, Coll Life Sci, Dept Bot, Changsha 410081, Hunan, Peoples R China. Peking Univ, Sch Adv Agr Sci, Peking Tsinghua Ctr Life Sci, State Key Lab Prot & Plant Gene Res, Beijing 100871, Peoples R China. He, GM Deng, XW (reprint author), Peking Univ, Sch Life Sci, Beijing 100871, Peoples R China. |
| Keywords | Allelic bias Arabidopsis gene expression H3K27me3 natural variation GENE-EXPRESSION GENOME-WIDE HISTONE H3 EPIGENOMIC VARIATION MESSENGER-RNA THALIANA DIVERGENCE MAIZE SEQ TRIMETHYLATION |
| Issue Date | 2016 |
| Publisher | JOURNAL OF INTEGRATIVE PLANT BIOLOGY |
| Citation | JOURNAL OF INTEGRATIVE PLANT BIOLOGY.2016,58,(5),466-474. |
| Abstract | Histone modifications affect gene expression, but the mechanism and biological consequence of natural variation in histone modifications remain unclear. Here, we generated genome-wide integrated maps of H3K27me3 modification and transcriptome for Col, C24 and their F-1 hybrid. A total of 1,828 genomic regions showing variation in H3K27me3 modification between Col and C24 were identified, most of which were associated with genic regions. Natural variation of H3K27me3 modification between parents could result in allelic bias of H3K27me3 in hybrids. Furthermore, we found that H3K27me3 variation between Col and C24 was negatively correlated with gene expression differences between two accessions, especially with those arising from the cis-effect. Importantly, mutation of CLF, an Arabidopsis methyltransferase for H3K27, altered gene expression patterns between the parents. Together, these data provide insights into natural variation of histone modifications and their association with gene expression differences between Arabidopsis ecotypes. |
| URI | http://hdl.handle.net/20.500.11897/417304 |
| ISSN | 1672-9072 |
| DOI | 10.1111/jipb.12443 |
| Indexed | SCI(E) PubMed 中国科技核心期刊(ISTIC) 中国科学引文数据库(CSCD) |
| Appears in Collections: | 现代农学院 生命科学学院 |
