| Title | The prevalence of erectile dysfunction among subjects with late-onset hypogonadism: a population-based study in China |
| Authors | Tang, Wen-Hao Zhuang, Xin-Jie Shu, Ru-Ming Guan, Di Ji, Yu-Dang Zhang, Bao-Long Wang, Can-Gang Zhuang, Li-Hua Yang, Zhuo Hong, Kai Ma, Lu-Lin Jiang, Hui Zhou, Shan-Jie Gu, Yi-Qun |
| Affiliation | Peking Univ, Dept Urol, Hosp 3, Beijing 100191, Peoples R China. Peking Univ, Reprod Med Ctr, Hosp 3, Beijing 100191, Peoples R China. First Hosp Nanchang, Dept Obstet & Gynaecol, Nanchang 330008, Peoples R China. Capital Med Univ, Beijing Tongren Hosp, Dept Urol, Beijing 100730, Peoples R China. Fucheng Tech Serv Ctr Family Planning, Fucheng 053700, Hebei, Peoples R China. Tianjin United Family Hosp, Reprod Med Ctr, Tianjin 300221, Peoples R China. Natl Res Inst Family Planning, Dept Male Clin Res, Natl Hlth & Family Planning Key Lab Male Reprod H, Beijing 100081, Peoples R China. Tianjin United Family Hosp, Reprod Med Ctr, 22 Tianxiao Yuan,Tanjiang Rd, Tianjin 300221, Peoples R China. |
| Keywords | Erectile dysfunction late-onset hypogonadism in males prevalence rate aging male community population INTERNATIONAL INDEX ANDROGEN DEFICIENCY NATIONAL-HEALTH SYMPTOMS MEN TESTOSTERONE MALES OLD |
| Issue Date | 2015 |
| Publisher | INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE |
| Citation | INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE.2015,8,(8),13901-13910. |
| Abstract | Introduction: The concurrence of chronic diseases and some well-defined risk factors significantly impacts the prevalence of erectile dysfunction (ED). Aim: To determine whether late-onset hypogonadism (LOH) impacts the prevalence of ED using investigation reproductive health data of middle-aged and aging males in China. Methods: The reproductive health status of 1498 males, aged 40-69 years, was evaluated using questionnaires of LOH based on the Androgen Deficiency in Aging Males (ADAM) and Aging Male Symptoms scale (AMS), as well as the International Index of Erectile Function-5 (IIEF-5) assessment. The 10th percentile of serum total testosterone (TT) and calculated free testosterone (cFT) levels of controls were set as cut-off levels of AD. The main outcome measures were used to assess the prevalence of LOH and ED according to different subject characteristics. Results: Of the 1472 subjects who completed the questionnaires who supplied hormone measurements, the prevalence of self-reported ED and identified by the IIEF-5 assessment were 11.28% and 77.85%, respectively. The IIEF-5 assessment revealed a prevalence of ED of 55.34%, 88.20%, and 91.77%, respectively, among those aged 40-49, 50-59, and 60-69 years. AD rates of ED subjects were 13.73% and 40.69% according to the TT and cFT cut-off levels. The prevalence of ED among subjects positive for LOH (ADAM+ and AMS+) were 88.81% and 95.80%, respectively. The prevalence of ED among the AD subjects (TT and cFT cut-off levels) with LOH (ADAM+ and AMS+) were 86.67%/81.82%. And the prevalence of ED among clinical LOH subjects (ADAM+ and AMS+) were 89.51%/98.48%. Conclusions: We found that middle-aged and aging Chinese males were at a relatively high risk of ED. The prevalence of ED among subjects with LOH symptoms was greater than in all recruited subjects. The effect of LOH on the prevalence of ED far outweighed the risk of decreased testosterone levels. |
| URI | http://hdl.handle.net/20.500.11897/416974 |
| ISSN | 1940-5901 |
| Indexed | SCI(E) PubMed |
| Appears in Collections: | 第三医院 |
