| Title | Safety of Spectacles for Children's Vision: A Cluster-Randomized Controlled Trial |
| Authors | Ma, Xiaochen Congdon, Nathan Yi, Hongmei Zhou, Zhongqiang Pang, Xiaopeng Meltzer, Miriam E. Shi, Yaopang He, Mingguang Liu, Yizhi Rozelle, Scott |
| Affiliation | Peking Univ, China Ctr Hlth Dev Studies, Beijing 100871, Peoples R China. Stanford Univ, Stanford Ctr Int Dev, Stanford, CA 94305 USA. Stanford Univ, Freeman Spogli Inst Int Studies, Stanford, CA 94305 USA. Sun Yat Sen Univ, State Key Lab Ophthalmol, Zhongshan Ophthalm Ctr, Guangzhou 510275, Guangdong, Peoples R China. ORBIS Int, New York, NY USA. Queens Univ Belfast, Ctr Publ Hlth, Belfast BT12 6AB, Antrim, North Ireland. Queens Univ Belfast, TREE Ctr, Belfast BT12 6AB, Antrim, North Ireland. Chinese Acad Sci, Ctr Chinese Agr Policy, Inst Geog Sci & Nat Resources Res, Beijing, Peoples R China. Renmin Univ China, Sch Agr Econ & Rural Dev, Beijing, Peoples R China. Shaanxi Normal Univ, Ctr Expt Econ Educ, Xian, Peoples R China. Queens Univ Belfast, TREE Ctr, Royal Victoria Hosp, Ctr Publ Hlth,Inst Clin Sci, Block N, Belfast BT12 6AB, Antrim, North Ireland. |
| Keywords | PEDIATRIC-REFRACTIVE-ERROR SECONDARY-SCHOOL STUDENTS MYOPIA PROGRESSION VISUAL IMPAIRMENT SOUTHERN CHINA RURAL CHINA LENSES PREVALENCE GLASSES |
| Issue Date | 2015 |
| Publisher | AMERICAN JOURNAL OF OPHTHALMOLOGY |
| Citation | AMERICAN JOURNAL OF OPHTHALMOLOGY.2015,160,(5),897-904. |
| Abstract | PURPOSE: To study safety of children's glasses in rural China, where fear that glasses harm vision is an important barrier for families and policy makers. DESIGN: Exploratory analysis from a cluster-randomized, investigator-masked, controlled trial. METHODS: Among primary schools (n = 252) in western China, children were randomized by school to 1 of 3 interventions: free glasses provided in class, vouchers for free glasses at a local facility, or glasses prescriptions only (Control group). The main outcome of this analysis is uncorrected visual acuity after 8 months, adjusted for baseline acuity. RESULTS: Among 19 934 children randomly selected for screening, 5852 myopic (spherical equivalent refractive error <=-0.5 diopters) eyes cif 3001 children (14.7%, mean age 10.5 years) had VA <= 6/12 without glasses correctable to >6/12 with glasses, and were eligible. Among these, 1903 (32.5%), 1798 (30.7%), and 2151 (36.8%) were randomized to Control, Voucher, and Free Glasses, respectively. Intention-to-treat analyses were performed on all 1831 (96.2%), 1699 (94.5%), and 2007 (93.3%) eyes of children with follow-up in Control, Voucher, and Free Glasses groups. Final visual acuity for eyes of children in the treatment groups (Free Glasses and Voucher) was significantly better than for Control children, adjusting only for baseline visual acuity (difference of 0.023 logMAR units [0.23 vision chart lines, 95% CI: 0.03, 0.43]) or for other baseline factors as well (0.025 logMAR units [0.25 lines, 95% CI 0.04, 0.45]). CONCLUSION: We found no evidence that spectacles promote decline in uncorrected vision with aging among children. (C) 2015 by Elsevier Inc. All rights reserved. |
| URI | http://hdl.handle.net/20.500.11897/415356 |
| ISSN | 0002-9394 |
| DOI | 10.1016/j.ajo.2015.08.013 |
| Indexed | SCI(E) PubMed |
| Appears in Collections: | 国家发展研究院 |
