| Title | Effects of radiofrequency ablation on lymphocyte subsets and type 1/type 2 T cell subpopulations in patients with hepatocellular carcinoma |
| Authors | Wang, Yan-bin Xu, Wei-Guo Liu, He-liang Yan, Kun Ma, Lin Guo, Wan-hou |
| Affiliation | N China Coal Med Univ, Affiliated Hosp, Dept Ultrasound, Tangshan 063000, Peoples R China. Peking Univ, Beijing Canc Hosp & Inst, Key Lab Carcinogenesis & Translat Res, Minist Educ,Dept Ultrasound,Sch Oncol, Beijing 100142, Peoples R China. |
| Keywords | Hepatocellular carcinoma Radiofrequency ablation Lymphocyte subsets T-lymphocyte subsets Th1/Th2 Tc1/Tc2 LIVER-TUMORS INTRACELLULAR CYTOKINES CANCER-PATIENTS |
| Issue Date | 2009 |
| Publisher | 中国癌症研究英文版 |
| Citation | CHINESE JOURNAL OF CANCER RESEARCH.2009,21,(4),310-317. |
| Abstract | To evaluate whether radiofrequency ablation (RFA) might have an influence on immune status in hepatocellular carcinoma (HCC) patients. We measured the T lymphocytes, B lymphocyte and NK cells, and determined the population of Th1, Th2, Tc1 and Tc2 of peripheral blood samples taken from 26 HCC patients before and after RFA. The proportion of Type1 cells (Th1 and Tc1) and NK cells were significantly increased after RFA, especially in patients of the following subgroups: male, age > 55 years, pathological grade I-II tumor, clinical stage I-II or Child-Pugh A and B. Type1 cells and NK cells in HCC patients were increased in a short period after RFA. |
| URI | http://hdl.handle.net/20.500.11897/396135 |
| ISSN | 1000-9604 |
| DOI | 10.1007/s11670-009-0310-6 |
| Indexed | SCI(E) 中国科技核心期刊(ISTIC) 中国科学引文数据库(CSCD) |
| Appears in Collections: | 北京肿瘤医院 |
