Title Gaining a comprehensive understanding of pruritus
Authors Zhang, Haiiao
Yang, Yi
Cui, Jiuwei
Zhang, Yaqin
Affiliation Jilin Univ, Dept Hematol Oncol, Hosp 1, Changchun 130023, Peoples R China.
Peking Univ, Dept Urol, Hosp 3, Beijing, Peoples R China.
Jilin Univ, Dept Dermatol, Hosp 2, Changchun 130023, Peoples R China.
218 Ziqiang St, Changchun 130041, Peoples R China.
Keywords Classification
pruritus
pathogenesis
treatment
CHRONIC IDIOPATHIC URTICARIA
BRAIN-SKIN CONNECTION
ATOPIC-DERMATITIS
INTRAHEPATIC CHOLESTASIS
UREMIC PRURITUS
UNKNOWN ORIGIN
CHRONIC ITCH
CUTANEOUS MANIFESTATIONS
HEMODIALYSIS-PATIENTS
URSODEOXYCHOLIC ACID
Issue Date 2012
Citation INDIAN JOURNAL OF DERMATOLOGY VENEREOLOGY & LEPROLOGY.2012,78,(5),532-544.
Abstract Pruritus is a common symptom associated with many dermatoses, systemic abnormalities, and psychiatric / psychosomatic diseases. Additionally, pruritus is one of the most intractable symptoms due to its complex pathogenesis involving an increasing number of mediators and receptors, undefined neurophysiologic pathways, unclear cerebral processing, and psychophysiology interaction. Clinically, the first challenge of dermatologists is how to get general and interdisciplinary vision of pruritus and to preliminarily figure it out whether there might be underlying systemic or psychosocial disorders. The second challenge is to select efficient individual tailored anti-pruritic treatment, which includes targeted drugs and cognitive-behavioral therapy.
URI http://hdl.handle.net/20.500.11897/392938
ISSN 0378-6323
DOI 10.4103/0378-6323.100516
Indexed SCI(E)
Appears in Collections: 第三医院

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