| Title | Milk consumption is a risk factor for prostate cancer in Western countries: evidence from cohort studies |
| Authors | Qin, Li-Qiang Xu, Ha-Ying Wang, Pei-Yu Tong, Han Hoshi, Kazuhiko |
| Affiliation | Peking Univ, Sch Publ Hlth, Dept Social Med & Hlth Educ, Beijing 100083, Peoples R China. Soochow Univ, Sch Radiat Med & Publ Hlth, Suzhou, Peoples R China. Univ Yamanashi, Sch Med, Dept Obstet & Gynecol, Chuo, Yamanashi, Japan. Peking Univ, Sch Publ Hlth, Dept Social Med & Hlth Educ, Xueyan Rd 38,Haidian Dist, Beijing 100083, Peoples R China. |
| Keywords | milk dairy products prostate cancer meta-analysis cohort study oriental populations DAIRY-PRODUCTS DIETARY-FAT ANIMAL PRODUCTS CALCIUM MEN METAANALYSIS JAPANESE HEALTH EPIDEMIOLOGY MORTALITY |
| Issue Date | 2007 |
| Publisher | asia pacific journal of clinical nutrition |
| Citation | ASIA PACIFIC JOURNAL OF CLINICAL NUTRITION.2007,16,(3),467-476. |
| Abstract | We have previously found a positive association between milk consumption and prostate cancer risk using metaanalysis to analyze published case-control studies. In the present study, further meta-analysis was conducted to estimate the summary relative risk (RR) between the consumption of milk and dairy products and prostate cancer from cohort studies published between 1966- 2006. We found 18 relevant articles and 13 independent studies were available for our analysis. The summary RR was 1.13 (95% confidence interval = 1.02-1.24) when comparing the highest with the lowest quantile of consumption. The summary RRs by study stratification showed a positive association. A dose-response relationship was identified when combining the studies that partitioned the consumption by quintiles. We also evaluated the effects of some limitations, such as dairy classification, prostate cancer stages and publication bias, in the present study. These findings, together with the previous study, suggest that the consumption of milk and dairy products increases the risk of prostate cancer. This is biologically plausible since milk contains considerable amounts of fat, hormones, and calcium that are associated with prostate cancer risk. |
| URI | http://hdl.handle.net/20.500.11897/345458 |
| ISSN | 0964-7058 |
| Indexed | SCI(E) PubMed |
| Appears in Collections: | 公共卫生学院 |
