| Title | A matched case-control study of risk factors in abdominal aortic aneurysm |
| Authors | Zuo Shang-wei Wei Ying-qi Chen Feng Chen Da-fang Wu Tao Liu Kuo Sun Ke-xin Juan Juan Xiong Jiang Guo Wei |
| Affiliation | Department of Vascular & Endovascular Surgery, PLA General Hospital, Beijing 100853, China. Department of Epidemiology and Biostatistics, Peking University School of Public Health, Beijing 100191, China. |
| Issue Date | 2014 |
| Publisher | 开云app体育 学报 医学版 |
| Citation | Beijing da xue xue bao. Yi xue ban.2014,46,(3),412-6. |
| Abstract | To examine the potential influence factors of abdominal aortic aneurysm (AAA).A 1:2 pair-matched, case-control study was conducted from July 2011 to December 2012. A pair was composed of one AAA patient recruited from the Vascular Surgery Department, Chinese PLA General Hospital and two gender- and age-matched non-AAA subjects, one from the same hospital and the other from the community in Fangshan District in Beijing. Demographic data, medical history and the lifestyle of each subject were collected. Moreover, all the participants underwent abdominal ultrasound or computed tomography (CT) and peripheral venous blood samples were obtained.There were 155 case/control pairs. The multivariate conditional logistic regression model confirmed that suffering from hypertension conferred a 1.98-fold (95%CI 1.12-3.18) increased likelihood of AAA. Smoking was a strong independent risk factor of AAA, with odds ratios (95% confidence intervals) of 5.23 (2.44-11.23). Dyslipidemia (OR=2.61,95% CI 1.45-4.70), a higher level of serum hsCRP (OR=2.43,95%CI 1.37-4.31) and homocysteine (OR=2.73,95% CI 1.61-4.65) were all associated with AAA.Hypertension and smoking are the risk factors of AAA. Dyslipidemia, hsCRP and Hcy are associated with AAA. |
| URI | http://hdl.handle.net/20.500.11897/342108 |
| ISSN | 1671-167X |
| Indexed | PubMed |
| Appears in Collections: | 公共卫生学院 |
