Title | A Hybrid IMRT/VMAT Technique for the Treatment of Nasopharyngeal Cancer |
Authors | Zhao, Nan Yang, Ruijie Jiang, Yuliang Tian, Suqing Guo, Fuxin Wang, Junjie |
Affiliation | Peking Univ, Dept Radiat Oncol, Hosp 3, Beijing 100191, Peoples R China. |
Keywords | VOLUMETRIC-MODULATED ARC SIMULTANEOUS INTEGRATED BOOST BEAM ANGLE OPTIMIZATION RADIATION-THERAPY NECK-CANCER RADIOTHERAPY CARCINOMA IMRT HEAD PROSTATE |
Issue Date | 2015 |
Publisher | biomed research international |
Citation | Biomed Research International.2015. |
Abstract | Hybrid IMRT/VMAT technique which combined intensity modulated radiotherapy (IMRT) and volumetricmodulated arc therapy (VMAT) was developed for the treatment of nasopharyngeal cancer (NPC). Two-full-arc VMAT (2ARC-VMAT), 9-field IMRT (9F-IMRT), and Hybrid IMRT/VMAT plans for NPC were compared in terms of the dosimetric quality, sparing of organs at risk (OARs), and delivery efficiency. The Hybrid IMRT/VMAT technique can improve the target dose homogeneity and conformity compared with 9F-IMRT and 2ARC-VMAT. It can reduce the dose delivered to the TMJ, mandible, temporal lobe, and unspecified tissue with fewer MUs compared with 9F-IMRT and dose delivered to parotids, brainstem, and spinal cord compared with 2ARC-VMAT technique. The mean delivery time of Hybrid plans was shorter than that of 9F-IMRT plans (408 s versus 812 s; P = 0.00) and longer than that of 2ARC-VMAT plans (408 s versus 179 s; P = 0.00). Hybrid IMRT/VMAT technique could be a viable radiotherapy technique with better plan quality. |
URI | http://hdl.handle.net/20.500.11897/341466 |
ISSN | 2314-6133 |
DOI | 10.1155/2015/940102 |
Indexed | SCI(E) PubMed |
Appears in Collections: | 第三医院 |