TitleA Hybrid IMRT/VMAT Technique for the Treatment of Nasopharyngeal Cancer
AuthorsZhao, Nan
Yang, Ruijie
Jiang, Yuliang
Tian, Suqing
Guo, Fuxin
Wang, Junjie
AffiliationPeking Univ, Dept Radiat Oncol, Hosp 3, Beijing 100191, Peoples R China.
KeywordsVOLUMETRIC-MODULATED ARC
SIMULTANEOUS INTEGRATED BOOST
BEAM ANGLE OPTIMIZATION
RADIATION-THERAPY
NECK-CANCER
RADIOTHERAPY
CARCINOMA
IMRT
HEAD
PROSTATE
Issue Date2015
Publisherbiomed research international
CitationBiomed Research International.2015.
AbstractHybrid IMRT/VMAT technique which combined intensity modulated radiotherapy (IMRT) and volumetricmodulated arc therapy (VMAT) was developed for the treatment of nasopharyngeal cancer (NPC). Two-full-arc VMAT (2ARC-VMAT), 9-field IMRT (9F-IMRT), and Hybrid IMRT/VMAT plans for NPC were compared in terms of the dosimetric quality, sparing of organs at risk (OARs), and delivery efficiency. The Hybrid IMRT/VMAT technique can improve the target dose homogeneity and conformity compared with 9F-IMRT and 2ARC-VMAT. It can reduce the dose delivered to the TMJ, mandible, temporal lobe, and unspecified tissue with fewer MUs compared with 9F-IMRT and dose delivered to parotids, brainstem, and spinal cord compared with 2ARC-VMAT technique. The mean delivery time of Hybrid plans was shorter than that of 9F-IMRT plans (408 s versus 812 s; P = 0.00) and longer than that of 2ARC-VMAT plans (408 s versus 179 s; P = 0.00). Hybrid IMRT/VMAT technique could be a viable radiotherapy technique with better plan quality.
URIhttp://hdl.handle.net/20.500.11897/341466
ISSN2314-6133
DOI10.1155/2015/940102
IndexedSCI(E)
PubMed
Appears in Collections:第三医院

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