Title Direct Growth of Human Enamel-Like Calcium Phosphate Microstructures on Human Tooth
Authors Wang, Xiaokun
Xia, Chunjie
Zhang, Zhouhao
Den, Xuliang
Wei, Shicheng
Zheng, Gang
Chen, Haifeng
Affiliation Peking Univ, Coll Engn, Dept Biomed Engn, Beijing 100871, Peoples R China.
Peking Univ, Sch & Hosp Stomatol, Beijing 100081, Peoples R China.
Peking Univ, Acad Adv Interdisciplinary Studies, Ctr Biomed Mat & Tissue Engn, Beijing 100871, Peoples R China.
Keywords Dental Enamel
Calcium Phosphate
Self-Assembly
NANORODS
REPAIR
Issue Date 2009
Citation JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY.2009/2/1,9(1361-1364).
Abstract Dental Enamel is the hardest mineralized tissue in the human body which is comprised of nanorod-like hydroxyapatite crystals arranged into a highly organized micro-architectural unit called an enamel prism. In this paper the direct growth of human enamel-like structures on human tooth using fluorapatite/phosphoric acid pastes is explored. SEM images show that the newly formed calcium phosphate crystals can be self-assembled into a similar ordered microstructure as those seen in human enamel. The mechanism of how these structures form is discussed. This work demonstrates the potential of applying nanotechnology to regenerate dental enamel clinically without cells.
URI http://hdl.handle.net/20.500.11897/316111
ISSN 1533-4880
DOI 10.1166/jnn.2009.C157
Indexed SCI(E)
EI
CPCI-S(ISTP)
Appears in Collections: 工学院
口腔医院
前沿交叉学科研究院

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