| Title | Reduced ventral anterior cingulate and amygdala volumes in medication-naive females with major depressive disorder: A voxel-based morphometric magnetic resonance imaging study |
| Authors | Tang, Yanqing Wang, Fei Xie, Guangrong Liu, Jun Li, Lehua Su, Linyan Liu, Ying Hu, Xian He, Zhong Blumberg, Hilary P. |
| Affiliation | S Cent Univ, Xiangya Hosp 2, Dept Psychiat, Changsha 410011, Peoples R China. China Med Univ, Affiliated Hosp 1, Dept Psychiat, Shenyang 110001, Peoples R China. Peking Univ, Natl Mental Hlth, Beijing 100083, Peoples R China. Yale Univ, Sch Med, Dept Psychiat, New Haven, CT 06511 USA. Dept Vet Affairs, West Haven, CT 06516 USA. S Cent Univ, Xiangya Hosp 2, Dept Psychiat, 86,Mid Renmin Rd, Changsha 410011, Peoples R China. |
| Keywords | major depressive disorder magnetic resonance imaging voxel-based morphometry SUBGENUAL PREFRONTAL CORTEX GRAY-MATTER VOLUME HIPPOCAMPAL VOLUME BIPOLAR DISORDER GLIAL REDUCTION MOOD DISORDERS |
| Issue Date | 2007 |
| Publisher | psychiatry research neuroimaging |
| Citation | PSYCHIATRY RESEARCH-NEUROIMAGING.2007,156,(1),83-86. |
| Abstract | High resolution magnetic resonance imaging and voxel-based morphometry were used to compare regional gray matter volumes between 14 medication-naive female participants with a first episode of major depressive disorder (MDD) and 13 female healthy comparison participants (HC). Volumes of bilateral ventral anterior cingulate cortex (vACC) and right amygdala were significantly smaller in the MDD group than in the HC group. These results suggest that volume reductions in vACC and amygdala in females with MDD are present at illness onset. (c) 2007 Elsevier Ireland Ltd. All rights reserved. |
| URI | http://hdl.handle.net/20.500.11897/252800 |
| ISSN | 0925-4927 |
| DOI | 10.1016/j.pscychresns.2007.03.005 |
| Indexed | SCI(E) |
| Appears in Collections: | 待认领 |
