| Title | Toward breast cancer resistance protein (BCRP) inhibitors: design, synthesis of a series of new simplified fumitremorgin C analogues |
| Authors | Wu, Guofeng Liu, Jiawang Bi, Lanrong Zhao, Ming Wang, Chao Baudy-Floc'h, Michele Ju, Jingfang Peng, Shiqi |
| Affiliation | Univ S Alabama, Mitchell Canc Inst, Mobile, AL 36688 USA. Capital Med Univ, Coll Pharmaceut Sci, Beijing 100069, Peoples R China. Peking Univ, Coll Pharmaceut Sci, Beijing 100083, Peoples R China. Univ Rennes 1, Grp Ciblage & Autoassemblages Fonctionels, CNRS, UMR 6226, F-35042 Rennes, France. Univ S Alabama, Mitchell Canc Inst, 307 N Univ Blvd, Mobile, AL 36688 USA. |
| Keywords | fumitremorgin C analogues breast cancer resistance protein inhibitors enantioselective synthesis racemization coupling MULTIDRUG-RESISTANCE DRUG-RESISTANCE SOLID-PHASE EFFLUX TRANSPORTERS COUPLING REAGENTS PEPTIDE-SYNTHESIS P-GLYCOPROTEIN MECHANISM REVERSAL CELLS |
| Issue Date | 2007 |
| Publisher | tetrahedron |
| Citation | TETRAHEDRON.2007,63,(25),5510-5528. |
| Abstract | In this study, we report the design and synthesis of a series of new simplified fumitremorgin C analogues. The preliminary biological study indicated some of these simplified fumitremorgin C might be developed into breast cancer resistance inhibitors. (c) 2007 Elsevier Ltd. All rights reserved. |
| URI | http://hdl.handle.net/20.500.11897/250268 |
| ISSN | 0040-4020 |
| DOI | 10.1016/j.tet.2007.04.045 |
| Indexed | SCI(E) |
| Appears in Collections: | 药学院 |
