| Title | Crush Stenting With Drug-Eluting Stents: Relevance of Coronary Bifurcation Lesion Location on Angiographic and Clinical Outcomes |
| Authors | Chen, Shao-Liang Zhang, Jun-jie Ye, Fei Liu, Zhi-zhong Zhu, Zhong-sheng Lin, Song Tian, Nai-liang Fang, Wei-yi Chen, Yun-dai Sun, Xue-wen Wei, Meng Shan, Shou-jie Kan, Jing Qian, Jun Yang, Song Yuan, Zeng-bai Kwan, Tak W. Hu, Da-Yi |
| Affiliation | Nanjing Med Univ, Nanjing Hosp 1, Nanjing, Peoples R China. Shanghai Chest Hosp, Shanghai, Peoples R China. Capital Med Univ, Beijing Anzhen Hosp, Beijing, Peoples R China. Huainan Dongfang Hosp, Huainan, Peoples R China. Shanghai 6th Hosp, Shanghai, Peoples R China. Maanshan Cent Hosp, Maanshan, Peoples R China. Yixin Peoples Hosp, Yixin, Peoples R China. Huaibei Mineral Gen Hosp, Huaibei, Peoples R China. Peking Univ, Peoples Hosp, Beijing 100871, Peoples R China. Nanjing Med Univ, Nanjing Hosp 1, 68 Changle Rd, Nanjing, Peoples R China. |
| Keywords | ARTERY BIFURCATION FOLLOW-UP REVASCULARIZATION REGISTRY ERA PREDICTORS IMMEDIATE STENOSIS INSIGHTS BRANCH |
| Issue Date | 2010 |
| Publisher | clinical cardiology |
| Citation | CLINICAL CARDIOLOGY.2010,33,(12),E32-E39. |
| Abstract | Background: Data on the relevance of the location of coronary bifurcation lesions treated by crush stenting with outcomes were limited. Hypothesis: We hypothesized that the location of the bifurcation lesion correlated with clinical outcome. Method: A total of 212 patients with 230 true bifurcation lesions treated by crush stenting with drug-eluting stents (DES) were assessed prospectively. Surveillance quantitative angiographies were indexed at 8 months after procedure. Primary endpoint was major adverse cardiac events (MACE), defined as cardiac death, myocardial infarction, and target lesion revascularization (TLR). Results: Patients in the distal right coronary artery (RCAd) group were characterized by higher proportions of prior myocardial infarction and very tortuous lesions. However, lesions in the RCAd group, compared to those of other groups, had the lowest late lumen loss, with resultant lowest incidence of MACE at a mean follow-up of 268 +/- 35 days. Independent predictors of MACE included unsatisfied kissing (KUS; hazard ratio [HR]: 12.14, 95% confidence interval [CI]: 4.01-12.10, P = .001) and non-RCA lesion (HR: 20.69, 95% CI: 5.05-22.38, P = .001), while those of TLR were KUS (HR: 10.21, 95% CI: 0.01-0.34, P = .002), bifurcation angle (HR: 4.728, 95% CI: 2.541-4.109, P = .001), and non-RCA lesion (HR: 16.05, 95% CI: 1.01-4.83, P = .001). Conclusions: Classical crush stenting with drug-eluting stents is associated with significantly better outcomes in RCAd. Quality of kissing inflation is mandatory to improve outcome. |
| URI | http://hdl.handle.net/20.500.11897/242016 |
| ISSN | 0160-9289 |
| DOI | 10.1002/clc.20544 |
| Indexed | SCI(E) |
| Appears in Collections: | 人民医院 |
